Evidence map›Paper›PMID 35028573›Full record

ArticleFood science of animal resources2022

Angiotensin-I-Converting Enzyme Inhibitory Peptides in Goat Milk Fermented by Lactic Acid Bacteria Isolated from Fermented Food and Breast Milk.

Yuliana Tandi Rubak, Lilis Nuraida, Dyah Iswantini, Endang Prangdimurti

Abstract read
In one paragraph

Article in Food science of animal resources, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuliana Tandi RubakDepartment of Food Science and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 16680, Indonesia.ORCID https://orcid.org/0000-0003-4685-1639
Lilis NuraidaDepartment of Food Science and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 16680, Indonesia.ORCID https://orcid.org/0000-0002-0847-5786
Dyah IswantiniDepartment of Chemistry, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 16680, Indonesia.ORCID https://orcid.org/0000-0003-1113-2722
Endang PrangdimurtiDepartment of Food Science and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 16680, Indonesia.ORCID https://orcid.org/0000-0002-1287-3031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, angiotensin-I-converting enzyme inhibitory (ACEI) activity was evaluated in fermented goat milk fermented by lactic acid bacteria (LAB) from fermented foods and breast milk. Furthermore, the potential for ACEI peptides was identified in fermented goat milk with the highest ACEI activity. The proteolytic specificity of LAB was also evaluated. The 2% isolate was inoculated into reconstituted goat milk (11%, w/v), then incubated at 37°C until pH 4.6 was reached. The supernatant produced by centrifugation was analyzed for ACEI activity and total peptide. Viable cell counts of LAB and titratable acidity were also evaluated after fermentation. Peptide identification was carried out using nano liquid chromatography mass spectrometry (LC-MS/MS), and potential as an ACEI peptide was carried out based on a literature review. The result revealed that ACEI activity was produced in all samples (20.44%-60.33%). Fermented goat milk of

Indexed as

angiotensin-I-converting enzyme (ACE) inhibitory activityantihypertensive peptidesgoat milk fermentedlactis BD17Lc. lactis sspproteolytic specificity

Identifiers

PMID35028573
PMCPMC8728504

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.