Effects of lighting environment on the degeneration of retinal ganglion cells in glutamate/aspartate transporter deficient mice, a mouse model of normal tension glaucoma.

Tsutomu Ohashi, Kazuhiko Namekata, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Takayuki Harada

Open access · goldAbstract read

In one paragraph

Article in Biochemistry and biophysics reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 57% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis.Investigative ophthalmology & visual science · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tsutomu OhashiOhashi Eye Center, Sapporo, Japan.

Kazuhiko NamekataVisual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Xiaoli GuoVisual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Atsuko KimuraVisual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Chikako HaradaVisual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Takayuki HaradaVisual Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Tokyo Metropolitan Institute of Medical Science · JPOhtsuka Eye Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lighting conditions may affect the development of retinal degenerative diseases such as macular degeneration. In this study, to determine whether the lighting environment affects the progression of degeneration of retinal ganglion cells (RGCs), we examined glutamate/aspartate transporter (GLAST) heterozygous (GLAST

Indexed as

GCL, ganglion cell layerGLAST deficient miceGLAST, glutamate/aspartate transporterGlaucomaIOP, intraocular pressureIRL, inner retinal layerLighting environmentmfERG, multifocal electroretinogramNeurodegenerationONL, outer nuclear layerRetinal ganglion cellRGC, retinal ganglion cell

Identifiers

PMID35028438

DOI10.1016/j.bbrep.2021.101197

PMCPMC8741416

OpenAlexW4206226851

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.