Evidence map›Paper›PMID 35028339›Full record

ArticleBone reports2022

Sex-specific differences in direct osteoclastic

Padmini Deosthale, Jung Min Hong, Alyson L Essex, Wilyaret Rodriguez, Dua Tariq, Harmandeep Sidhu, Alejandro Marcial, Angela Bruzzaniti, Lilian I Plotkin

Open access · goldAbstract read
In one paragraph

Article in Bone reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Independent contribution of gonads and sex chromosomes to sex differences in bone mass and strength in the four-core genotypes mouse model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Padmini DeosthaleDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Jung Min HongDepartment of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, USA.
Alyson L EssexDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Wilyaret RodriguezDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Dua TariqDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Harmandeep SidhuDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Alejandro MarcialDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Angela BruzzanitiDepartment of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, USA.
Lilian I PlotkinDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, USA.
Indiana University School of MedicineIndiana Hemophilia and Thrombosis Center · USIndiana University · USRichard L. Roudebush VA Medical Center · US

Funding

Comprehensive Training Program in Musculoskeletal ResearchT32AR065971 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI ALEXANDER G ROBLING · 2015 to 2026
$4.4M
Osteocyte Apoptosis and Regulation of Bone Resorption with AgingR01AR067210 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI PLOTKIN, LILIAN IRENE · 2015 to 2019
$1.9M
Connexin 43 Hemichannels and Signaling In BoneR01AR053643 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI PLOTKIN, LILIAN IRENE · 2008 to 2012
$1.6M
NIAMS NIH HHS R01 AR053643NIAMS NIH HHS R01 AR067210NIAMS NIH HHS T32 AR065971
6 · The paper itself

Abstract

Pannexin1 (Panx1) is a hemichannel-forming protein that participates in the communication of cells with the extracellular space. To characterize the role of osteoclastic Panx1 on bone, Panx1

Indexed as

Bone massBone resorptionOsteoclastPannexin

Identifiers

PMID35028339
PMCPMC8739454
OpenAlexW4206764103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.