Evidence map›Paper›PMID 35028080›Full record

ArticleJournal of dental sciences2022

Bone-related polymorphisms and dental status in older men and women. Results of the longitudinal Pro.V.A. study.

Estella Musacchio, Pierluigi Binotto, Fatima Silva-Netto, Egle Perissinotto, Leonardo Sartori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Estella MusacchioDepartment of Medicine DIMED, University of Padova, Padova, Italy.
Pierluigi BinottoDental Clinic Binotto Srl, via M. Polo 10, Padova, Italy.
Fatima Silva-NettoDepartment of Medicine DIMED, University of Padova, Padova, Italy.
Egle PerissinottoDepartment of Cardiologic, Thoracic and Vascular Sciences - Unit of Biostatistics, Epidemiology and Public Health - University of Padova, Padova, Italy.
Leonardo SartoriDepartment of Medicine DIMED, University of Padova, Padova, Italy.
University of Padua · ITGiotto Biotech (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeGenetics plays a role in the susceptibility to periodontitis and tooth loss. Several studies examined the involvement of polymorphisms in candidate genes. We hypothesize that bone metabolism-related polymorphisms could be associated with the number of remaining teeth. MATERIALS AND

methodsParticipants in the Pro.V.A. longitudinal Study: 3099 Italians (aged 65+ at baseline), 2196 at follow-up 1 (5yrs), 1641 at follow-up 2 (7yrs) underwent detailed interview and clinical-instrumental examination. Subjects, grouped by remaining teeth number (0, 1-7, 8-19, 20+), were genotyped for six different bone-related polymorphisms: collagen type Iα1 (COL1A1, Sp1,

resultsCOL1A1 associated with dental status:

conclusionThe present study, demonstrating an association between tooth loss and COL1A1 and -in men- CALCR, contributes to the identification of genes involved in tooth loss and, possibly, susceptibility to periodontitis.

Indexed as

BoneGenetic polymorphismsOral healthTooth lossType I collagen

Identifiers

PMID35028080
PMCPMC8740094
OpenAlexW3192224783

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.