Evidence map›Paper›PMID 35028045›Full record

ArticleJournal of dental sciences2022

Effect of nanosilver mouthwash on prevention of white spot lesions in patients undergoing fixed orthodontic treatment - a randomized double-blind clinical trial.

Azheen Ali, Hadi Ismail, Kawa Amin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Trial
  7. Trial
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  9. Journal of dentistry (Shiraz, Iran) · 2026
    Article
  10. Article
  11. Review
  12. Review
  13. Usage of Silver Nanoparticles in Orthodontic Bonding Reagents.Journal of functional biomaterials · 2025
    Review
  14. Article
  15. Mapping the Dental Applications of Nanosilver Fluoride: A Narrative Review.International journal of clinical pediatric dentistry · 2024
    Review
  16. Review
  17. Article
  18. Mouthwashes: Alternatives and Future Directions.International dental journal · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Azheen AliDepartment of Orthodontics, College of Dentistry, University of Sulaimani, Sulaimanyah, Iraq.
Hadi IsmailDepartment of Orthodontics, College of Dentistry, University of Sulaimani, Sulaimanyah, Iraq.
Kawa AminDepartment of Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq.
University of Sulaimani · IQUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeThe formation of white spot lesions (WSLs) around fixed orthodontic attachments is a common complication during and following fixed orthodontic treatment, marking the result of a successfully completed treatment. This double-blind, randomized clinical trial study aims to investigate the varying effects of nano-silver, chlorhexidine (CHX) or fluoride mouthwashes on WSLs. MATERIALS AND

methodsDouble-blind prospective randomized clinical trial, comprised of forty-two patients with mild to moderate crowding, were recruited for this study. Randomization and allocation to trial group were carried out by computer system in college of dentistry, university of Sulaimani from January 2020 to September 2020. The patients were divided into three groups (14 per group) according to the type of mouthwash used during the treatment (nano-silver, CHX or fluoride), using block randomization. The clinical examination for the presence of WSLs was recorded through visual examination of the upper and lower anterior teeth using the International Caries Detection and Assessment System (ICDAS II) score before bonding and at 30, 90 and 180 days after bonding of the upper and lower arches.

resultsThe total number of patients was 42 (16 males and 26 females) with a mean age of 23.02 ± 3.841 (18-37) years old, distributed into three groups of 14 patients. There is significant difference in white spot lesions formation between the three groups; the mean of WSLs in nanosilver group is lower than CHX and fluoride group in 90 and 180 days of follow-up (P < 0.05).

conclusionNano-silver mouthwash is more effective than CHX and fluoride mouthwash in reducing WSLs during orthodontic treatment.

Indexed as

ChlorhexidineDental cariesFluorideMouthwashNanosilver particlesOrthodontic appliances

Identifiers

PMID35028045
PMCPMC8739266
OpenAlexW3158689637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.