Evidence map›Paper›PMID 35027976›Full record

ArticleJournal of medicine and life

Early prenatal diagnosis of an atypical phenotype of sacral spina bifida.

Roxana Elena Bohîlțea, Bianca Margareta Mihai, Octavian Munteanu, Ioniță Ducu, Vasile Adrian Dumitru, Consuela-Mădălina Gheorghe, Tiberiu Augustin Georgescu, Valentin Varlas, Radu Vlădăreanu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Roxana Elena BohîlțeaDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Bianca Margareta MihaiDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, Bucharest, Romania.
Octavian MunteanuDepartment of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Bucharest, Romania.
Ioniță DucuDepartment of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Bucharest, Romania.
Vasile Adrian DumitruDepartment of Pathology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Consuela-Mădălina GheorgheDepartment of Marketing and Medical Technology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Tiberiu Augustin GeorgescuDepartment of Pathology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Valentin VarlasDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Radu VlădăreanuDepartment of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Clinical Emergency Hospital Bucharest · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural tube defects (NTDs) occur during embryogenesis, specifically during the fifth or sixth week of gestation, and are described as aberrant neural tube closing. The defect may alter the normal development of the vertebrae, spinal cord, cranium, or brain. The present study describes the case of a 41-year-old pregnant woman with fetal sacral meningocele, no associated pathologies, no family history of neural tube defects, a pregnancy under folate supplementation with the aim of highlighting the importance of ultrasound in diagnosing neural tube defects. The ultrasonographic diagnosis was not clear from the beginning. In our case, the differential diagnosis of meningocele was made with the cystic compound of a sacrococcygeal teratoma, which represents one of the most common congenital tumors in newborns. The particularity of this case was that a neural tube defect occurred despite the prophylactic administration of folic acid during pregnancy, which represents a well-documented protection against neural tube defects in fetuses.

Indexed as

Neural Tube DefectsSpinal DysraphismAdultFemaleFolic AcidHumansInfant, NewbornPhenotypePregnancyPrenatal DiagnosisFolic Acid2D ultrasonography – two-dimensional ultrasonographyembryogenesismeningoceleneural tube defectsNTDs – neural tube defectsSARS-COV 2 maternal infectionSARS-COV 2 – severe acute respiratory syndrome coronavirus 2ultrasonographic diagnosis

Identifiers

PMID35027976
PMCPMC8742886
OpenAlexW4205769261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.