Evidence map›Paper›PMID 35027848›Full record

ArticleCancer management and research2022

Machine Learning-Based Model for the Prognosis of Postoperative Gastric Cancer.

Donghui Liu, Xuyao Wang, Long Li, Qingxin Jiang, Xiaoxue Li, Menglin Liu, Wenxin Wang, Enhong Shi, Chenyao Zhang, Yinghui Wang and 2 more

Abstract read
In one paragraph

Article in Cancer management and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Research progress of machine learning applications in gastric cancer diagnosis and therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  9. The Role of Neural Network Analysis in Identifying Predictors of Gastric Cancer.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Donghui LiuSchool of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province, People's Republic of China.ORCID 0000-0002-5963-5372
Xuyao WangDepartment of Pharmacy, Harbin Second Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Long LiDepartment of General Surgery, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People's Republic of China.
Qingxin JiangDepartment of General Surgery, Harbin 242 Hospital of Genertec Medical, Harbin, Heilongjiang Province, People's Republic of China.
Xiaoxue LiDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Menglin LiuDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Wenxin WangDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Enhong ShiDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Chenyao ZhangDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Yinghui WangDepartment of Oncology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang Province, People's Republic of China.
Yan Zhang *School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province, People's Republic of China.
Liru Wang *School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of machine learning (ML) in predicting disease prognosis has increased, and scientists have adopted different methods for cancer classification to optimize the early screening of cancer to determine its prognosis in advance. In this study, we aimed at improving the prediction accuracy of gastric cancer in postoperation patients by constructing a highly effective prognostic model.

methodsThe study used postoperative gastric cancer patient data from the SEER database. The LASSO regression method was used to construct a clinical prognostic model, and four machine learning methods (Boruta algorithm, neural network, support vector machine, and random forest) were used to screen and recombine the features to construct an ML prognostic model. Clinical information on 955 postoperative gastric cancer patients collected from the Affiliated Tumor Hospital of Harbin Medical University was used for external verification.

resultsExperimental results showed that the AUC values of 1, 3 and 5 years in the training set, validation set and external validation set of clinical prognosis model and ML prognosis model directly established by LASSO regression are all around 0.8.

conclusionBoth models can accurately evaluate the prognosis of postoperative patients with gastric cancer, which may be helpful for accurate and personalized treatment of postoperative patients with gastric cancer.

Indexed as

BorutaElasticNetgastric cancermachine learningprognosisrandom forestSVM

Identifiers

PMID35027848
PMCPMC8752070

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