Evidence map›Paper›PMID 35027830›Full record

ArticleTherapeutics and clinical risk management2022

Prognostic Implications of the Admission Cardiac Troponin I Levels and Door-to-Balloon Time on Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention.

Longguo Zhao, Minglong Xin, Xianji Piao, Shengming Zhang, Yanglong Li, Xian Wu Cheng

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Longguo ZhaoDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.
Minglong XinDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.
Xianji PiaoDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.
Shengming ZhangDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.
Yanglong LiDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.
Xian Wu ChengDepartment of Cardiology and Hypertension, Yanbian University Hospital, Yanji, Jilin, 133000, People's Republic of China.ORCID 0000-0002-9758-0632
Yanbian University Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic implications of the admission cTnI level and D2B time combined on in-hospital and 1-year heart failure (HF) and mortality in STEMI patients undergoing a primary percutaneous coronary intervention (PCI) are remain uncertain. METHODS AND

resultsWe divided the consecutive 1485 STEMI patients who underwent PCI from January 2015 to October 2019 at our hospital into three groups based on their admission cTnI levels: normal group (<0.1 ng/mL), middle group (0.1 to less than 3 ng/mL), and high group (≥3 ng/mL) and into two groups by their D2B times: >90 min (>90-D2B) and ≤90 min (≤90-D2B). During the in-hospital and 1-year follow-up periods, the incidence of composite clinical events increased significantly with the increase in the admission cTnI level (p < 0.05). In-hospital, the composite rate of death and HF events was significantly higher in the >90-D2B group compared to the ≤90-D2B group (p = 0.006), but its influence disappeared in the 1-year follow-up (p > 0.05). A multivariable logistic analysis revealed that, in the ≤90-D2B group, with the exception of the cTnI ≥3 ng/mL patients, the cTnI level had no effect on in-hospital or 1-year outcomes; in >90-D2B group, cTnI ≥3ng/mL increased outcomes in both periods.

conclusionHigh cTnI levels (≥3 ng/mL) on admission are independent of the D2B time for predicting in-hospital and 1-year cardiac events in STEMI patients undergoing PCI.

Indexed as

acute myocardial infarctioncardiac deathcardiac troponin Idoor-to-balloon timeheart failure

Identifiers

PMID35027830
PMCPMC8752064
OpenAlexW4205533573

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.