Evidence map›Paper›PMID 35027822›Full record

ArticlePatient preference and adherence2022

Polypharmacy, Medication-Related Burden and Antiretroviral Therapy Adherence in People Living with HIV Aged 50 and Above: A Cross-Sectional Study in Hunan, China.

Chunyuan Zheng, Jingjing Meng, Xueling Xiao, Ying Xie, Di Zhao, Honghong Wang

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chunyuan ZhengXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.
Jingjing MengXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.
Xueling XiaoXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.
Ying XieXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.
Di ZhaoXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-5599-9451
Honghong WangXiangya Nursing School, Central South University, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-3484-8929
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePeople living with HIV (PLWHIV) are susceptible to non-communicable diseases (NCDs) because of aging and infections. This means that the number of non-HIV medications increases, along with issues of polypharmacy and medication-related burden. The purpose of this study was to identify the current situation of polypharmacy and medication-related burden among PLWHIV aged 50 and above, as well as the relation between medication-related burden and antiretroviral therapy (ART) adherence. PATIENTS AND

methodsA cross-sectional study was conducted with 185 participants recruited from two HIV clinics in Yuelu District Center for Disease Control (CDC) and Changsha First Hospital in Hunan, China. Participants filled questionnaires about comorbidities, polypharmacy, medication-related burden, ART adherence and sociodemographic characteristics.

resultsAmong the participants, 40% were receiving polypharmacy, and PLWHIV, who were female (

conclusionThe findings suggest that more attention should be paid to the issues of polypharmacy and targeted interventions should be developed to reduce medication-related burden among older PLWHIV.

Indexed as

agingAIDScomorbiditymedication adherencemedication burdenpotential drug–drug interaction

Identifiers

PMID35027822
PMCPMC8752076
OpenAlexW4205115996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.