Evidence map›Paper›PMID 35027642›Full record

ArticleScientific reports2022

Post-stroke treatment with argon preserved neurons and attenuated microglia/macrophage activation long-termly in a rat model of transient middle cerebral artery occlusion (tMCAO).

Jingjin Liu, Michael Veldeman, Anke Höllig, Kay Nolte, Lisa Liebenstund, Antje Willuweit, Karl-Josef Langen, Rolf Rossaint, Mark Coburn

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Positive Effects of Argon Inhalation After Traumatic Brain Injury in Rats.International journal of molecular sciences · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jingjin Liu *Department of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany.
Michael Veldeman *Department of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany.
Anke HölligDepartment of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany.
Kay NolteDepartment of Neuropathology, University RWTH Aachen, Aachen, Germany.
Lisa LiebenstundDepartment of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany.
Antje WilluweitInstitute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich, Germany.
Karl-Josef LangenInstitute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich, Germany.
Rolf RossaintDepartment of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany.
Mark CoburnDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany. mark.coburn@ukbonn.de.
RWTH Aachen University · DEForschungszentrum Jülich · DEUniversity Hospital Bonn · DE

Funding

Deutsche Forschungsgemeinschaft CO 799/9-1
6 · The paper itself

Abstract

In a previous study from our group, argon has shown to significantly attenuate brain injury, reduce brain inflammation and enhance M

Indexed as

Neuroprotective AgentsAnimalsArgonDisease Models, AnimalInfarction, Middle Cerebral ArteryMacrophage ActivationRatsTime FactorsTime-to-TreatmentArgonNeuroprotective Agents

Identifiers

PMID35027642
PMCPMC8758662
OpenAlexW4206837315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.