ArticleNature communications2022
Bridging pico-to-nanonewtons with a ratiometric force probe for monitoring nanoscale polymer physics before damage.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 91 citations in OpenAlex.
- Force-Induced Control of Circularly Polarized Luminescence With Rotaxane Architecture.Angewandte Chemie (International ed. in English) · 2026Article
- Modeling Targeted Mechanochemistry in Polymeric Solids.Chemical reviews · 2026Review
- Cyclic Tetraindoles with a Cyclooctatetraene Core: Controlling Planarity and Antiaromatic Character via N-Alkylation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Optical Force Monitoring in Polymeric Materials with a Coumarin-Based Mechanophore.Angewandte Chemie (International ed. in English) · 2025Article
- Hinge-Like Mechanochromic Mechanophores Based on [2.2]Paracyclophane.Angewandte Chemie (International ed. in English) · 2025Article
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- Advancing the Mechanosensitivity of Atropisomeric Diarylethene Mechanophores through a Lever-Arm Effect.Journal of the American Chemical Society · 2025Article
- Mechanistically Different Mechanochromophores Enable Calibration and Validation of Molecular Forces in Glassy Polymers and Elastomeric Networks.Angewandte Chemie (International ed. in English) · 2024Article
- Molecular Probing of the Microscopic Pressure at Contact Interfaces.Journal of the American Chemical Society · 2024Article
- Mechanochromic polymer blends made with an excimer-forming telechelic sensor molecule.Soft matter · 2024Article
- Nanomechanical Mapping of Three Dimensionally Printed Poly-ε-Caprolactone Single Microfibers at the Cell Scale for Bone Tissue Engineering Applications.Biomimetics (Basel, Switzerland) · 2023Article
- Environment-sensitive fluorescence of COT-fused perylene bisimide based on symmetry-breaking charge separation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Article
- Highly Stretchable Stress-Strain Sensor from Elastomer Nanocomposites with Movable Cross-links and Ketjenblack.ACS polymers Au · 2023Article
- Thermally Stable Photomechanical Molecular Hinge: Sterically Hindered Stiff-Stilbene Photoswitch Mechanically Isomerizes.JACS Au · 2023Article
- Microscopic strain mapping in polymers equipped with non-covalent mechanochromic motifs.Materials horizons · 2023Article
- Force-Triggered Atropisomerization of a Parallel Diarylethene to Its Antiparallel Diastereomers.Journal of the American Chemical Society · 2023Article
- Functionalized Hydrogel-Based Wearable Gas and Humidity Sensors.Nano-micro letters · 2023Review
- Swelling-Activated, Soft Mechanochemistry in Polymer Materials.Langmuir : the ACS journal of surfaces and colloids · 2023Review
- Excited State Charge-Transfer Complexes Enable Fluorescence Color Changes in a Supramolecular Cyclophane Mechanophore.Angewandte Chemie (International ed. in English) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Understanding the transmission of nanoscale forces in the pico-to-nanonewton range is important in polymer physics. While physical approaches have limitations in analyzing the local force distribution in condensed environments, chemical analysis using force probes is promising. However, there are stringent requirements for probing the local forces generated before structural damage. The magnitude of those forces corresponds to the range below covalent bond scission (from 200 pN to several nN) and above thermal fluctuation (several pN). Here, we report a conformationally flexible dual-fluorescence force probe with a theoretically estimated threshold of approximately 100 pN. This probe enables ratiometric analysis of the distribution of local forces in a stretched polymer chain network. Without changing the intrinsic properties of the polymer, the force distribution was reversibly monitored in real time. Chemical control of the probe location demonstrated that the local stress concentration is twice as biased at crosslinkers than at main chains, particularly in a strain-hardening region. Due to the high sensitivity, the percentage of the stressed force probes was estimated to be more than 1000 times higher than the activation rate of a conventional mechanophore.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.