Evidence map›Paper›PMID 35026112›Full record

ArticleNano letters2022

Cation-Responsive and Photocleavable Hydrogels from Noncanonical Amphiphilic DNA Nanostructures.

Giacomo Fabrini, Aisling Minard, Ryan A Brady, Marco Di Antonio, Lorenzo Di Michele

Abstract read
In one paragraph

Article in Nano letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Internal Phase Separation in Synthetic DNA Condensates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Enzyme-Responsive DNA Condensates.Journal of the American Chemical Society · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Self-Assembly of DNA Nanostructures in Different Cations.Small (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  16. Article
  17. Self-assembly of DNA nanostructures in different cations.bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Review
  20. Reaction-Diffusion Patterning of DNA-Based Artificial Cells.Journal of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giacomo FabriniDepartment of Chemistry, Imperial College London, London W12 0BZ, United Kingdom.
Aisling MinardDepartment of Chemistry, Imperial College London, London W12 0BZ, United Kingdom.
Ryan A BradyDepartment of Chemistry, King's College London, London SE1 1DB, United Kingdom.ORCID 0000-0002-0408-3224
Marco Di AntonioDepartment of Chemistry, Imperial College London, London W12 0BZ, United Kingdom.ORCID 0000-0002-7321-1867
Lorenzo Di MicheleDepartment of Chemistry, Imperial College London, London W12 0BZ, United Kingdom.ORCID 0000-0002-1458-9747

Funding

Biotechnology and Biological Sciences Research Council BB/R011605/1
6 · The paper itself

Abstract

Thanks to its biocompatibility, versatility, and programmable interactions, DNA has been proposed as a building block for functional, stimuli-responsive frameworks with applications in biosensing, tissue engineering, and drug delivery. Of particular importance for in vivo applications is the possibility of making such nanomaterials responsive to physiological stimuli. Here, we demonstrate how combining noncanonical DNA G-quadruplex (G4) structures with amphiphilic DNA constructs yields nanostructures, which we termed "Quad-Stars", capable of assembling into responsive hydrogel particles via a straightforward, enzyme-free, one-pot reaction. The embedded G4 structures allow one to trigger and control the assembly/disassembly in a reversible fashion by adding or removing K

Indexed as

G-QuadruplexesNanostructuresCationsDNAHydrogelsCationsDNAHydrogelsAmphiphilic DNADNA nanotechnologyG-quadruplexesself-assemblystimuli-responsive hydrogels

Identifiers

PMID35026112
PMCPMC8796241

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.