Evidence map›Paper›PMID 35026040›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022

Primary prevention recommendations to reduce the risk of cognitive decline.

Marwan N Sabbagh, Adriana Perez, Thomas M Holland, Malaz Boustani, Stephanie R Peabody, Kristine Yaffe, Michelle Bruno, Russell Paulsen, Kelly O'Brien, Naila Wahid and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  6. System changes to empower primary care in Alzheimer's disease detection and care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Marwan N SabbaghBarrow Neurological Institute, Dignity Health/St Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Adriana PerezLeonard Davis Institute of Health Economics at the University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA.
Thomas M HollandRush University Medical Center, Chicago, Illinois, USA.
Malaz BoustaniIndiana University Center for Health Innovation and Implementation Science, School of Medicine, Indianapolis, Indiana, USA.
Stephanie R PeabodyBrain Health Initiative, Lakewood Ranch, Florida, USA.
Kristine YaffeUniversity of California San Francisco, San Francisco, California, USA.
Michelle BrunoAvalere Health, Washington, District of Columbia, USA.
Russell PaulsenUsAgainstAlzheimer's, Washington, District of Columbia, USA.
Kelly O'BrienUsAgainstAlzheimer's, Washington, District of Columbia, USA.
Naila WahidAvalere Health, Washington, District of Columbia, USA.
Rudolph E TanziMcCance Center for Brain Health, Massachusetts General Hospital, Boston, MA USA, Boston, Massachusetts, USA.
Prevea Health · USUsAgainstAlzheimer · USBarrow Neurological Institute · USIndiana University – Purdue University Indianapolis · USMassachusetts General Hospital · USRush University Medical Center · USUniversity of California, San Francisco · USUniversity of Pennsylvania · USWomen's Health Initiative · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFew resources address steps clinicians can take to help patients reduce their risk of dementia, despite growing recognition that brain health can be optimized and that risk reduction for cognitive decline can be accomplished by lifestyle modifications.

methodsTo address this gap, UsAgainstAlzheimer's convened a risk reduction workgroup (RRWG) to review existing evidence and develop recommendations for primary care clinicians discussing cognitive decline and risk reduction with their patients. 

resultsThe RRWG produced 11 consensus-based recommendations and implementation strategies across six topics: neurovascular risk management, physical activity, sleep, nutrition, social isolation, and cognitive stimulation.  DISCUSSION: These recommendations are a first step for clinicians to address brain health with patients and potentially help them prevent cognitive decline. To ensure there is routine care for brain health, proper incentives and policies must be instituted and more education for consumers should be provided.

Indexed as

Cognitive DysfunctionExerciseHumansLife StylePrimary PreventionRisk Reduction BehaviorAlzheimer's diseasecognitive declinedementia preventionprimary carerisk reduction

Identifiers

PMID35026040
PMCPMC9545398
OpenAlexW4206572467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.