Evidence map›Paper›PMID 35025966›Full record

ArticlePloS one2022

The Symptom Burden and Quality of Life in Cancer Patients in the Gaza Strip, Palestine: A Cross-Sectional Study.

Yousuf ElMokhallalati, Enas Alaloul, Mohammed Shatat, Tasneem Shneewra, Saad El Massri, Omar Shaer, Samuel Relton, Hammoda Abu-Odah, Matthew J Allsop

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Cancer pain and its impact on quality of life, distress, and spiritual well-being in the war-torn Gaza Strip.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Dynamic Network Analysis of Symptom Profiles and Their Expected Impact on Patients with Colorectal Cancer Receiving Postoperative Adjuvant Chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Beyond Measurement: Strengthening HRQOL Research in Cancer.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Yousuf ElMokhallalatiLeeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, United Kingdom.
Enas AlaloulLeeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, United Kingdom.
Mohammed ShatatMinistry of Health, Gaza, occupied Palestinian territory.
Tasneem ShneewraMinistry of Health, Gaza, occupied Palestinian territory.
Saad El MassriFaculty of Medicine, Islamic University, Gaza, occupied Palestinian territory.
Omar ShaerFaculty of Medicine, Islamic University, Gaza, occupied Palestinian territory.ORCID 0000-0002-0583-4800
Samuel ReltonLeeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, United Kingdom.ORCID 0000-0003-0634-4587
Hammoda Abu-OdahSchool of Nursing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.ORCID 0000-0002-8874-2599
Matthew J AllsopLeeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, United Kingdom.ORCID 0000-0002-7399-0194
University of Leeds · GBIslamic University of Gaza · PSMinistry of Health · JMHong Kong Polytechnic University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCancer is the second leading cause of death in the Gaza Strip, Palestine, but there is an absence of evidence systematically assessing symptom burden and quality of life (QoL) using validated tools. Our objective was to assess associations between socio-demographic and disease-related characteristics, symptom burden and QoL in a sample of cancer patients accessing outpatient services in the Gaza Strip.

designA cross-sectional, descriptive survey using interviews and medical record review involving patients with cancer accessing oncology outpatient services at Al Rantisi Hospital and European Gaza Hospital (EGH) in the Gaza Strip was employed. Socio-demographic and disease-related data, the Lebanese version of the Memorial Symptom Assessment Scale (MSAS-Leb), and the Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) were collected. Multiple linear regression was used to judge the relative influence of determinants of QoL.

resultsOf 414 cancer patients approached, 385 patients consented to participation. The majority were women (64.7%) with a mean age of 52 years (SD = 16.7). Common cancer diagnoses were breast (32.2%), haematological (17.9%) and colorectal (9.1%). The median number of symptoms was 10 (IQR 1.5-18.5). Mean overall QoL was 70.5 (SD 19.9) with common physical and psychological symptoms identified. A higher burden of symptoms was associated with marital status, education and income. Limited access to both opioids and psychological support were reported.

conclusionsA high symptom burden was identified in outpatients with cancer. Increasing provision and access to supportive care for physical and psychological symptoms should be prioritised alongside exploring routine assessment of symptom burden and QoL.

Indexed as

Cost of IllnessAdultAgedArabsCross-Sectional StudiesFemaleHumansMaleMiddle AgedMiddle EastNeoplasmsOutpatientsPsychometricsQuality of LifeSociodemographic FactorsSurveys and Questionnaires

Identifiers

PMID35025966
PMCPMC8758072
OpenAlexW4206535066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.