SynthesisPloS one2022
Asthma control and its predictors in Ethiopia: Systematic review and meta-analysis.
Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Treatment response and determinants of asthma control in Eastern Africa.BMC pulmonary medicine · 2026Article
- Clinical Remission in Severe Asthma: A Comparative Analysis of Patients with and Without Biologics from the Swiss Severe Asthma Registry.Biomedicines · 2025Article
- The Establishment of a Registry of Respiratory Patients Attending Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Feasibility Study.Ethiopian journal of health sciences · 2025Article
- Improving Inhaler Technique through Face-to-Face and Multimedia Training: A QI Project in an Ethiopian Chest Clinic.Ethiopian journal of health sciences · 2025Article
- Reliability of the Amharic Version of the Medication Adherence Report Scale and Beliefs about Medicines Questionnaire in Patients with Asthma in Ethiopia.Ethiopian journal of health sciences · 2025Article
- Assessment of asthma control levels in a tertiary hospital: A cross-sectional study.Saudi medical journal · 2025Article
- Effectiveness of inhaled therapies in asthma among adults in Northern Sri Lanka, a low-income and middle-income country: a prospective observational study.BMJ open respiratory research · 2025Observational
- Scaling up noncommunicable disease care in a resource-limited context: lessons learned and implications for policy.BMC health services research · 2024Article
- Prevalence of medication adherence among adult asthmatic patients in four African countries: A systematic review and meta-analysis.The World Allergy Organization journal · 2024Review
- Patient autonomy in self-managing their bronchial asthma exacerbation and its associated factors, 2024.Frontiers in allergy · 2024Article
- Factors influencing health-related quality of life in children with asthma: insights from Addis Ababa public hospitals.Frontiers in public health · 2024Article
- Trends, seasonal variations and forecasting of chronic respiratory disease morbidity in charcoal producing areas, northwest Ethiopia: time series analysis.Frontiers in epidemiology · 2024Article
- One size does not fit all: an application of stochastic modeling to estimating primary healthcare needs in Ethiopia at the sub-national level.BMC health services research · 2023Article
- Percent Recovery Index Predicts Poor Asthma Control and Exacerbation in Adults.Journal of asthma and allergy · 2023Article
- Autophagy-Related Genes Are Involved in the Progression and Prognosis of Asthma and Regulate the Immune Microenvironment.Frontiers in immunology · 2022Article
- Identification of pyroptosis-related subtypes and establishment of prognostic model and immune characteristics in asthma.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDetermining the status of asthma control and identifying risk factors for poor asthma control is a key strategy for curbing the negative health impacts and the financial burden of the disease. Therefore, this review was aimed to determine the rate of asthma control and assess the predictors of uncontrolled asthma in Ethiopia.
methodsPubMed, Web of Science, and Google Scholar searches were performed using key terms; "asthma, bronchial asthma, control, controlled, uncontrolled and Ethiopia" up to October 16, 2020. University repositories were also searched to retrieve gray literature. The results were presented as a prevalence rate with a 95% confidence interval (CI). Subgroup analysis and meta-regression were performed to identify the sources of heterogeneity in the outcomes.
resultsFrom 1,388 patients, based on the Global Initiative for Asthma (GINA) symptom control, the rate of the uncontrolled asthma was 45.0% (95% CI 34.0% - 56.0%) with a considerable heterogeneity between the studies; (I2: 94.55, p< 0.001). About 19.0% (95% CI 10.0% - 29.0%); (I2: 96.04, p< 0.001) of the asthma patients had a well-controlled asthma. Moreover, 36.0% (95% CI 22.0% - 50.0%), (I2: 97.11, p< 0.001) of patients had a partly controlled asthma. Similarly, based on the asthma control test (ACT), the rate of well-controlled asthma was 22.0% (95% CI 3% - 42.0%), with considerable heterogeneity between the studies; (I2: 97.75, p< 0.001). The most frequent predictors of uncontrolled asthma were incorrect inhalation techniques, frequent SABA use, moderate/severe persistent asthma, history of exacerbations, presence of comorbidities, use of oral corticosteroids, and irregular follow-up.
conclusionThe rate of uncontrolled asthma in Ethiopia was high. Several factors are associated with uncontrolled asthma. Comprehensive asthma educations at each follow-up visit should be strengthened to minimize the morbidity and the cost of uncontrolled asthma.
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