Evidence map›Paper›PMID 35025923›Full record

ArticlePloS one2022

Identifying barriers to ART initiation and adherence: An exploratory qualitative study on PMTCT in Zambia.

Tukiya Kanguya, Aybüke Koyuncu, Anjali Sharma, Thankian Kusanathan, Martha Mubanga, Benjamin H Chi, Michael J Vinikoor, Mwangelwa Mubiana-Mbewe

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Tukiya KanguyaCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.
Aybüke KoyuncuCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.ORCID 0000-0002-3060-6279
Anjali SharmaCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.
Thankian KusanathanDepartment of Gender Studies, University of Zambia, Lusaka, Zambia.
Martha MubangaCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.
Benjamin H ChiUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-1435-8455
Michael J VinikoorUniversity of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Mwangelwa Mubiana-MbeweCentre for Infectious Diseases Research in Zambia, Lusaka, Zambia.ORCID 0000-0002-7122-842X
Centre for Infectious Disease Research in Zambia · ZMUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity of Zambia · ZM

Funding

CGH CDC HHS U01 GH000530
6 · The paper itself

Abstract

backgroundThough antiretroviral therapy (ART) is widely available, HIV positive pregnant women in Zambia are less likely to start and remain on therapy throughout pregnancy and after delivery. This study sought to understand readiness to start ART among HIV pregnant women from the perspectives of both women and men in order to suggest more holistic programs to support women to continue life-long ART after delivery.

methodsWe conducted a qualitative study with HIV positive pregnant women before and after ART initiation, and men with female partners, to understand readiness to start lifelong ART. We conducted 28 in-depth interviews among women and 2 focus group discussions among male partners. Data were transcribed verbatim and analyzed in NVivo 12 using thematic analysis. Emerging themes from the data were organized using the social ecological framework.

resultsMen thought of their female partners as young and needing their supervision to initiate and stay on ART. Women agreed that disclosure and partner support were necessary preconditions to ART initiation and adherence and, expressed fear of divorce as a prominent barrier to disclosure. Maternal love and desire to look after one's children instilled a sense of responsibility among women which motivated them to overcome individual, interpersonal and health system level barriers to initiation and adherence. Women preferred adherence strategies that were discrete, the effectiveness of which, depended on women's intrinsic motivation.

conclusionThe results support current policies in Zambia to encourage male engagement in ART care. To appeal to male partners, messaging on ART should be centered on emphasizing the importance of male involvement to ensure women remain engaged in ART care. Programs aimed at supporting postpartum ART adherence should design messages that appeal to both men's role in couples' joint decision-making and women's maternal love as motivators for adherence.

Indexed as

AdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveDrug MonitoringFemaleFocus GroupsHIV InfectionsHumansInfectious Disease Transmission, VerticalMaleMedication AdherencePatient CompliancePregnancyPregnancy Complications, InfectiousPregnant PeopleQualitative ResearchAnti-HIV Agents

Identifiers

PMID35025923
PMCPMC8757984
OpenAlexW4206767409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.