Evidence map›Paper›PMID 35025865›Full record

ArticlePLoS neglected tropical diseases2022

Effects of vaccination and non-pharmaceutical interventions and their lag times on the COVID-19 pandemic: Comparison of eight countries.

Hao Li, Luqi Wang, Mengxi Zhang, Yihan Lu, Weibing Wang

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness of social distancing measures and lockdowns for reducing transmission of COVID-19 in non-healthcare, community-based settings.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Pooled it
  3. Review
  4. Implementation evaluation of the COVID-19 vaccination: Speed, equity and mortality trends.African journal of primary health care & family medicine · 2026
    Article
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  12. Observational
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  18. [Association of public health and social measures with the effectiveness of COVID-19 epidemic control].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao LiSchool of Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-7212-557X
Luqi WangSchool of Public Health, Fudan University, Shanghai, China.
Mengxi ZhangSchool of Public Health, Fudan University, Shanghai, China.
Yihan LuSchool of Public Health, Fudan University, Shanghai, China.
Weibing WangSchool of Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-4497-5251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many countries implemented measures to control the COVID-19 pandemic, but the effects of these measures have varied greatly. We evaluated the effects of different policies, the prevalence of dominant variants (e.g., Delta), and vaccination on the characteristics of the COVID-19 pandemic in eight countries. We quantified the lag times of different non-pharmaceutical interventions (NPIs) and vaccination using a distributed lag non-linear model (DLNM). We also tested whether these lag times were reasonable by analyzing changes in daily cases and the effective reproductive number (Rt)over time. Our results indicated that the response to vaccination in countries with continuous vaccination programs lagged by at least 40 days, and the lag time for a response to NPIs was at least 14 days. A rebound was most likely to occur during the 40 days after the first vaccine dose. We also found that the combination of school closure, workplace closure, restrictions on mass gatherings, and stay-at-home requirements were successful in containing the pandemic. Our results thus demonstrated that vaccination was effective, although some regions were adversely affected by new variants and low vaccination coverage. Importantly, relaxation of NPIs soon after implementation of a vaccination program may lead to a rebound.

Indexed as

COVID-19 VaccinesVaccinationAgedBasic Reproduction NumberCOVID-19HumansImmunization ProgramsMass GatheringsPandemicsSARS-CoV-2SchoolsVaccination CoverageCOVID-19 Vaccines

Identifiers

PMID35025865
PMCPMC8757886

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.