Evidence map›Paper›PMID 35025860›Full record

SynthesisPLoS neglected tropical diseases2022

Machine learning and deep learning techniques to support clinical diagnosis of arboviral diseases: A systematic review.

Sebastião Rogério da Silva Neto, Thomás Tabosa Oliveira, Igor Vitor Teixeira, Samuel Benjamin Aguiar de Oliveira, Vanderson Souza Sampaio, Theo Lynn, Patricia Takako Endo

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Forecasting and Early Warning Systems for Dengue Outbreaks: Updated Narrative Review.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Quantitative detection of chikungunya, Zika, and dengue viruses by one-step real-time PCR in different cell substrates.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sebastião Rogério da Silva NetoUniversidade de Pernambuco, Recife, Brazil.ORCID 0000-0001-8109-697X
Thomás Tabosa OliveiraUniversidade de Pernambuco, Recife, Brazil.ORCID 0000-0001-8224-5922
Igor Vitor TeixeiraUniversidade de Pernambuco, Recife, Brazil.ORCID 0000-0002-5334-884X
Samuel Benjamin Aguiar de OliveiraUniversidade do Estado do Amazonas, Manaus, Brazil.ORCID 0000-0002-4821-8100
Vanderson Souza SampaioUniversidade do Estado do Amazonas, Manaus, Brazil.ORCID 0000-0001-7307-8851
Theo LynnDublin City University, Dublin, Ireland.
Patricia Takako EndoUniversidade de Pernambuco, Recife, Brazil.ORCID 0000-0002-9163-5583
Universidade de Pernambuco · BRFundação de Medicina Tropical · BRDublin City University · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeglected tropical diseases (NTDs) primarily affect the poorest populations, often living in remote, rural areas, urban slums or conflict zones. Arboviruses are a significant NTD category spread by mosquitoes. Dengue, Chikungunya, and Zika are three arboviruses that affect a large proportion of the population in Latin and South America. The clinical diagnosis of these arboviral diseases is a difficult task due to the concurrent circulation of several arboviruses which present similar symptoms, inaccurate serologic tests resulting from cross-reaction and co-infection with other arboviruses.

objectiveThe goal of this paper is to present evidence on the state of the art of studies investigating the automatic classification of arboviral diseases to support clinical diagnosis based on Machine Learning (ML) and Deep Learning (DL) models.

methodWe carried out a Systematic Literature Review (SLR) in which Google Scholar was searched to identify key papers on the topic. From an initial 963 records (956 from string-based search and seven from a single backward snowballing procedure), only 15 relevant papers were identified.

resultsResults show that current research is focused on the binary classification of Dengue, primarily using tree-based ML algorithms. Only one paper was identified using DL. Five papers presented solutions for multi-class problems, covering Dengue (and its variants) and Chikungunya. No papers were identified that investigated models to differentiate between Dengue, Chikungunya, and Zika.

conclusionsThe use of an efficient clinical decision support system for arboviral diseases can improve the quality of the entire clinical process, thus increasing the accuracy of the diagnosis and the associated treatment. It should help physicians in their decision-making process and, consequently, improve the use of resources and the patient's quality of life.

Indexed as

Decision Support Systems, ClinicalAedesAnimalsArbovirus InfectionsChikungunya FeverChikungunya virusDeep LearningDengueDengue VirusHumansMosquito VectorsNeglected DiseasesSouth AmericaZika VirusZika Virus Infection

Identifiers

PMID35025860
PMCPMC8791518
OpenAlexW4206294008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.