Evidence map›Paper›PMID 35025012›Full record

ArticleSleep & breathing = Schlaf & Atmung2022

Sleep-related hypoventilation and hypercapnia in multiple system atrophy detected by polysomnography with transcutaneous carbon dioxide monitoring.

Atsuhiko Sugiyama, Jiro Terada, Yu Shionoya, Shigeki Hirano, Tatsuya Yamamoto, Yoshitaka Yamanaka, Nobuyuki Araki, Ken Koshikawa, Hajime Kasai, Shinobu Ikeda and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A strategic approach of the management of sleep-disordered breathing in multiple system atrophy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Pooled it
  2. Nocturnal hypercapnia in obstructive sleep apnoea and obesity hypoventilation: from pathophysiology to measurement and treatment.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Non-invasive PCOSleep & breathing = Schlaf & Atmung · 2025
    Article
  4. Impact of supine body position on sleep-disordered breathing in patients with MSA patients.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Atsuhiko SugiyamaDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan. asugiyama@chiba-u.jp.ORCID 0000-0003-0705-9892
Jiro TeradaDepartment of Pulmonary Medicine, School of Medicine, International University of Health and Welfare (IUHW), Chiba, Japan.
Yu ShionoyaDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shigeki HiranoDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Tatsuya YamamotoDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Yoshitaka YamanakaDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Nobuyuki ArakiDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Ken KoshikawaDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hajime KasaiDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shinobu IkedaDivision of Laboratory Medicine, Chiba University Hospital, Chiba, Japan.
Jiaqi WangDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Kyosuke KoideDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Shoichi ItoDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Satoshi KuwabaraDepartment of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Chiba University · JPChiba Prefectural University of Health Sciences · JPChiba University Hospital · JPInternational University of Health and Welfare · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate sleep-related hypoventilation in multiple system atrophy (MSA) using polysomnography (PSG) with transcutaneous partial pressure of carbon dioxide (PtcCO

methodsThis prospective study included 34 patients with MSA. Motor and autonomic function, neuropsychological tests, PSG with PtcCO

resultsNine (27%) of the 34 patients met the diagnostic criteria of SRHD. Twenty-nine (85%) patients had sleep-related breathing disorders based on an Apnea-Hypopnea Index of ≥ 5/h. The patients with MSA and SRHD had a higher arousal index (p = 0.017) and obstructive apnea index (p = 0.041) than those without SRHD. There was no difference in the daytime partial pressure of carbon dioxide in arterial blood or respiratory function between MSA patients with and without SRHD.

conclusionSleep-related hypoventilation may occur in patients with MSA even with a normal daytime partial pressure of carbon dioxide. This can be noninvasively detected by PSG with PtcCO

Indexed as

Multiple System AtrophySleep Wake DisordersApneaCarbon DioxideHumansHypercapniaHypoventilationPolysomnographyProspective StudiesSleepCarbon DioxideCarbon dioxideHypercapniaNeuropsychological testsRespirator function testsSleep

Identifiers

PMID35025012
PMCPMC8756414
OpenAlexW4205531351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.