Evidence map›Paper›PMID 35024693›Full record

ReviewAndrogens: clinical research and therapeutics2021

Androgen Effects on Neural Plasticity.

Nariko Kuwahara, Kate Nicholson, Lauren Isaacs, Neil J MacLusky

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Androgens: clinical research and therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nariko KuwaharaDepartment of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Kate NicholsonDepartment of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Lauren IsaacsDepartment of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Neil J MacLuskyDepartment of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID https://orcid.org/0000-0002-9202-0564

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgens are synthesized in the brain, gonads, and adrenal glands, in both sexes, exerting physiologically important effects on the structure and function of the central nervous system. These effects may contribute to the incidence and progression of neurological disorders such as autism spectrum disorder, schizophrenia, and Alzheimer's disease, which occur at different rates in males and females. This review briefly summarizes the current state of knowledge with respect to the neuroplastic effects of androgens, with particular emphasis on the hippocampus, which has been the focus of much of the research in this field.

Indexed as

gliahippocampusneurosteroidogenesissynaptogenesistestosterone

Identifiers

PMID35024693
PMCPMC8744448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.