Evidence map›Paper›PMID 35024378›Full record

ArticleMolecular therapy. Methods & clinical development2022

VikAD, a Vika site-specific recombinase-based system for efficient and scalable helper-dependent adenovirus production.

Stacia Phillips, Paula Valino Ramos, Priyadharishini Veeraraghavan, Samuel M Young

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Presynaptic αNeuron · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stacia PhillipsDepartment of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, PBDB 5322, 169 Newton Road, Iowa City, IA 52242, USA.
Paula Valino RamosDepartment of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, PBDB 5322, 169 Newton Road, Iowa City, IA 52242, USA.
Priyadharishini VeeraraghavanDepartment of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, PBDB 5322, 169 Newton Road, Iowa City, IA 52242, USA.
Samuel M YoungDepartment of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, PBDB 5322, 169 Newton Road, Iowa City, IA 52242, USA.
University of Iowa · US

Funding

Regulation of Synaptic Vesicle Dynamics in the Auditory SystemR01DC014093 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOUNG, SAMUEL MATTHEW · 2015 to 2024
$3.7M
Presynaptic regulation of neurotransmitter release in mammalian neuronal circuitsR01NS110742 · NINDS · UNIVERSITY OF IOWA · PI YOUNG, SAMUEL MATTHEW · 2020 to 2024
$1.7M
Development of Helper Dependent Adenoviral Vectors for Inner Ear Gene Therapy ApproachesR21DC018242 · NIDCD · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, YOUNG, SAMUEL MATTHEW · 2019 to 2020
$425k
NIDCD NIH HHS R01 DC014093NIDCD NIH HHS R21 DC018242NINDS NIH HHS R01 NS110742
6 · The paper itself

Abstract

Recombinant viral vectors have become integral tools for basic

Indexed as

adenoviruscell-type-specific expressiongenetic intersectional strategieshelper-dependent adenovirusproductionsite-specific recombinasesviral vectors

Identifiers

PMID35024378
PMCPMC8718833
OpenAlexW4200298272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.