Evidence map›Paper›PMID 35024185›Full record

ArticleJournal of advanced research2021

Daisy Sotero Chacon, Taffarel Melo Torres, Ivanice Bezerra da Silva, Thiago Ferreira de Araújo, Alan de Araújo Roque, Francisco Ayrton Senna Domingos Pinheiro, Denise Selegato, Alan Pilon, Fernanda Priscila Santos Reginaldo, Cibele Tesser da Costa and 14 more

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The Integration of the Metabolome and Transcriptome forMolecules (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Transcriptome Analysis ofFrontiers in plant science · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 3 countries.

Daisy Sotero ChaconDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Taffarel Melo TorresBioinformatics, Biostatistics and Computer Biology Nucleus, Rural Federal University of the Semiarid, Mossoró, RN, Brazil.
Ivanice Bezerra da SilvaDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Thiago Ferreira de AraújoDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Alan de Araújo RoqueInstitute for Sustainable Development and Environment, Dunas Park Herbarium, Natal, RN, Brazil.
Francisco Ayrton Senna Domingos PinheiroDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Denise SelegatoMagnetic Resonance Center (CERM), University of Florence, Sesto Fiorentino, FI, Italy.
Alan PilonFaculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (FCFRP-USP), Ribeirão Preto, SP, Brazil.
Fernanda Priscila Santos ReginaldoDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Cibele Tesser da CostaPlant Physiology Laboratory, Center for Biotechnology and Department of Botany, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Johnatan VilasboaPlant Physiology Laboratory, Center for Biotechnology and Department of Botany, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Rafael Teixeira FreireSignal and Information Processing for Sensing Systems, Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, Barcelona, Spain.
Eduardo Luiz VoigtDepartment of Cell Biology and Genetics, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
José Angelo Silveira ZuanazziLaboratory of Pharmacognosy, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Renata LibonatiDepartment of Meteorology, Institute of Geoscience, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Julia Abrantes RodriguesDepartment of Meteorology, Institute of Geoscience, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Filippe Lemos Maia SantosDepartment of Meteorology, Institute of Geoscience, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Kátia Castanho ScortecciDepartment of Cell Biology and Genetics, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Norberto Peporine LopesFaculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (FCFRP-USP), Ribeirão Preto, SP, Brazil.
Leandro De Santis FerreiraDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Leandro Vieira Dos SantosBrazilian Biorenewables National Laboratory (LNBR), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, Brazil.
Alberto José CavalheiroChemistry Institute, São Paulo State University (UNESP), Araraquara, SP, Brazil.
Arthur Germano Fett-NetoPlant Physiology Laboratory, Center for Biotechnology and Department of Botany, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Raquel Brandt GiordaniDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Federal do Rio Grande do Sul · BRUniversidade Federal do Rio de Janeiro · BRUniversidade de Ribeirão Preto · BRBrazilian Center for Research in Energy and Materials · BRCentro Universitário de Araraquara · BRInstitute for Bioengineering of Catalonia · ESInteruniversity Consortium for Magnetic Resonance · ITUniversidade Federal Rural do Semi-Árido · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Natural products of pharmaceutical interest often do not reach the drug market due to the associated low yields and difficult extraction. Knowledge of biosynthetic pathways is a key element in the development of biotechnological strategies for plant specialized metabolite production. Objectives: In this sense, in an unprecedented approach used with a non-model Fabaceae species grown in its unique arid natural habitat, a combined transcriptome and metabolome analyses (seeds and leaves) is presented. Methods: The Next Generation Sequencing-based transcriptome ( Results: This detailed macro and micromolecular approach applied to seeds and leaves of Conclusion: Overall, these results could contribute by indicating potential biotechnological targets for modulation of erythrina alkaloids biosynthesis as well as improve molecular databases with omic data from a non-model medicinal plant, and reveal an interesting chemical diversity of

Indexed as

AlkaloidsErythrinaGene Expression ProfilingPlant LeavesSeedsTandem Mass SpectrometryAlkaloidsBenzylisoquinoline AlkaloidsCaatingaErythrina velutinaTargeted metabolite profileTranscriptome

Identifiers

PMID35024185
PMCPMC8655131
OpenAlexW3127388611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.