Evidence map›Paper›PMID 35024159›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Functional intermuscular reduction in spasticity for people with multiple sclerosis.

Bobbette J Miller, Thubi Ha Kolobe, Rebecca D Larson, Brian A Pribble, Gabriel Pardo, Shirley A James

Abstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bobbette J MillerDepartment of Rehabilitation Sciences, College of Allied Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.ORCID https://orcid.org/0000-0001-7629-6782
Thubi Ha KolobeDepartment of Rehabilitation Sciences, College of Allied Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Rebecca D Larson
Brian A PribbleDepartment of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.
Gabriel PardoOklahoma Medical Research Foundation, Multiple Sclerosis Center of Excellence, Oklahoma City, Oklahoma, USA.ORCID https://orcid.org/0000-0002-2207-3708
Shirley A JamesDepartment of Rehabilitation Sciences, College of Allied Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.ORCID https://orcid.org/0000-0002-1808-4957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEighty-five percent of people with multiple sclerosis (MS) incur gait impairments debilitating enough to significantly impact their function.

objectivesThe aim of this study was to determine if a novel combination of intermuscular electrical stimulation, followed by functional electrical stimulation combined with supported bodyweight treadmill training, would improve gait, decrease spasticity and fatigue, and improve muscle strength.

methodsUsing a pre-post experimental design, we implemented this combination six-week protocol in 16 individuals with MS. We completed summary statistics and longitudinal pre-post results using Wilcoxon sign rank tests with Bonferroni adjustment.

resultsParticipants responded with median increases of 29.4 feet (

conclusionsResults of this novel protocol suggest this intervention combination has the potential to decrease spasticity, and improve gait speed and endurance in individuals with MS. Observed changes in mobility occurred without accompanying increases in fatigue.

Indexed as

dry needlingfunctional electrical stimulationgaitMultiple sclerosis rehabilitationphysical outcomesspasticitytreadmill training

Identifiers

PMID35024159
PMCPMC8743971

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.