ArticleJournal of oral microbiology2022
Assessing the drug resistance profiles of oral probiotic lozenges.
Article in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Analysis of Antibiotic Susceptibility of Lactobacillus Strains Isolated from Adolescent Gut Microbiota.Bulletin of experimental biology and medicine · 2026Article
- Assessing the Antibiotic Resistance in Food Lactic Acid Bacteria: Risks in the Era of Widespread Probiotic Use.Food science & nutrition · 2025Review
- Modulation of the Human Microbiome: Probiotics, Prebiotics, and Microbial Transplants.Advances in experimental medicine and biology · 2025Review
- The Whole-Genome Sequencing and Probiotic Profiling ofNutrients · 2024Article
- Accounting for the health risk of probiotics.Heliyon · 2024Review
- Manipulating the diseased oral microbiome: the power of probiotics and prebiotics.Journal of oral microbiology · 2024Review
- Potential probiotic lactobacilli strains isolated from artisanal Mexican Cocido cheese: evidence-based biosafety and probiotic action-related traits on in vitro tests.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Antibiotic resistance in potential probiotic lactic acid bacteria of fermented foods and human origin from Nigeria.BMC microbiology · 2023Article
- ProbResist: a database for drug-resistant probiotic bacteria.Database : the journal of biological databases and curation · 2022Article
- Hydrogen Peroxide Activated by Biochar-Supported Sulfidated Nano Zerovalent Iron for Removal of Sulfamethazine: Response Surface Method Approach.International journal of environmental research and public health · 2022Article
- Editorial: Antimicrobial Resistance Along the Food Chain: Are We What We Eat?Frontiers in microbiology · 2022Article
- Characterization ofScience progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProbiotic lozenges have been developed to harvest the benefits of probiotics for oral health, but their long-term consumption may encourage the transfer of resistance genes from probiotics to commensals, and eventually to disease-causing bacteria.
aimTo screen commercial probiotic lozenges for resistance to antibiotics, characterize the resistance determinants, and examine their transferability
resultsProbiotics of all lozenges were resistant to glycopeptide, sulfonamide, and penicillin antibiotics, while some were resistant to aminoglycosides and cephalosporins. High minimum inhibitory concentrations (MICs) were detected for streptomycin (>128 µg/mL) and chloramphenicol (> 512 µg/mL) for all probiotics but only one was resistant to piperacillin (MIC = 32 µg/mL). PCR analysis detected erythromycin (
conclusionOur study represents the first antibiotic resistance profiling of probiotics from oral lozenges, thus highlighting the health risk especially in the prevailing threat of drug resistance globally.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.