Evidence map›Paper›PMID 35024088›Full record

ArticleJournal of oral microbiology2022

Arginine-induced metabolomic perturbation in

Yudong Liu, Shanshan Liu, Qinghui Zhi, Peilin Zhuang, Rongxiu Zhang, Zhenzhen Zhang, Kai Zhang, Yu Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Arginine inhibits cross-kingdom interactions and synergistic cariogenicity betweenFrontiers in cellular and infection microbiology · 2025
    Article
  7. Article
  8. Article
  9. Correlation between caries activity and salivary microbiota in preschool children.Frontiers in cellular and infection microbiology · 2023
    Article
  10. Article
  11. Genomic and phenotypic characterization ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yudong LiuDepartment of Histology and Embryology, Bengbu Medical College, Bengbu, China.
Shanshan LiuAnhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu, China.
Qinghui ZhiDepartment of Preventive Dentistry, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-Sen University, Guangzhou, China.
Peilin ZhuangDepartment of Stomatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Rongxiu ZhangDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Zhenzhen ZhangDepartment of Stomatology, Bengbu Medical College, Bengbu, China.
Kai ZhangDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Yu SunDepartment of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, China.
Bengbu Medical College · CNFirst Affiliated Hospital of Bengbu Medical College · CNStomatology Hospital · CNSun Yat-sen Memorial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo assess the impact of arginine-induced metabolomic perturbations on

methodsWe identified 5,933 and 7,413 ions in positive (ESI+) and negative (ESI-) electrospray ion modes, respectively, with a total of 11.05% and 11.58% differential ions subsequently detected in two respective modes. Further analyses of these metabolites led to identification of 8 and 22 metabolic pathways that were affected by arginine treatment in ESI+ and ESI- modes.

resultsOnce or twice daily treatments of

conclusionsArginine can reduce

Indexed as

arginineLiquid chromatography-tandem mass spectroscopymetabolomicStreptococcus mutans

Identifiers

PMID35024088
PMCPMC8745357
OpenAlexW4206368503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.