Evidence map›Paper›PMID 35024015›Full record

ArticleContrast media & molecular imaging2021

Predicting the Grade of Prostate Cancer Based on a Biparametric MRI Radiomics Signature.

Li Zhang, Xia Zhe, Min Tang, Jing Zhang, Jialiang Ren, Xiaoling Zhang, Longchao Li

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li ZhangDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.
Xia ZheDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.ORCID 0000-0003-4946-1302
Min TangDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.ORCID 0000-0002-4070-7110
Jing ZhangDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.ORCID 0000-0001-5901-5969
Jialiang RenGE Health Care, Beijing 100000, China.ORCID 0000-0001-5616-7035
Xiaoling ZhangDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.ORCID 0000-0001-8459-6259
Longchao LiDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710000, China.ORCID 0000-0001-8172-3371
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate the value of biparametric magnetic resonance imaging (bp-MRI)-based radiomics signatures for the preoperative prediction of prostate cancer (PCa) grade compared with visual assessments by radiologists based on the Prostate Imaging Reporting and Data System Version 2.1 (PI-RADS V2.1) scores of multiparametric MRI (mp-MRI). Methods: This retrospective study included 142 consecutive patients with histologically confirmed PCa who were undergoing mp-MRI before surgery. MRI images were scored and evaluated by two independent radiologists using PI-RADS V2.1. The radiomics workflow was divided into five steps: (a) image selection and segmentation, (b) feature extraction, (c) feature selection, (d) model establishment, and (e) model evaluation. Three machine learning algorithms (random forest tree (RF), logistic regression, and support vector machine (SVM)) were constructed to differentiate high-grade from low-grade PCa. Receiver operating characteristic (ROC) analysis was used to compare the machine learning-based analysis of bp-MRI radiomics models with PI-RADS V2.1. Results: In all, 8 stable radiomics features out of 804 extracted features based on T2-weighted imaging (T2WI) and ADC sequences were selected. Radiomics signatures successfully categorized high-grade and low-grade PCa cases ( Conclusions: The results of this clinical study indicate that machine learning-based analysis of bp-MRI radiomic models may be helpful for distinguishing high-grade and low-grade PCa that outperformed the PI-RADS V2.1 scores based on mp-MRI. The machine learning algorithm RF model was slightly better.

Indexed as

Multiparametric Magnetic Resonance ImagingProstatic NeoplasmsHumansMachine LearningMagnetic Resonance ImagingMaleRetrospective Studies

Identifiers

PMID35024015
PMCPMC8718299
OpenAlexW4200393780

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.