Evidence map›Paper›PMID 35023941›Full record

ArticleClinical, cosmetic and investigational dermatology2022

Vitiligo-Like Lesions in a Patient with Metastatic Breast Cancer Treated with Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor: A Case Report and Literature Review.

Baha' Sharaf, Rama AlMasri, Nayef Abdel-Razeq, Osama Salama, Ibrahim Hamad, Mahmoud Abunasser, Hikmat Abdel-Razeq

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Baha' SharafDepartment of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.ORCID 0000-0003-4368-1224
Rama AlMasriDepartment of Internal Medicine, Istishari Hospital, Amman, Jordan.
Nayef Abdel-RazeqDepartment of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA.
Osama SalamaDepartment of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.
Ibrahim HamadDepartment of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.ORCID 0000-0002-0234-5024
Mahmoud AbunasserDepartment of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.ORCID 0000-0002-8682-227X
Hikmat Abdel-RazeqDepartment of Internal Medicine, King Hussein Cancer Center, Amman, Jordan.ORCID 0000-0003-2833-6051
King Hussein Cancer Center · JOHenry Ford Hospital · USJordan Hospital · JOUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCyclin-dependent kinase (CDK) 4/6 inhibitors have revolutionized the treatment landscape of hormone receptor-positive (HR CASE PRESENTATION: A 71-year-old female patient was diagnosed initially with early-stage right breast cancer (HR

conclusionCDK4/6 inhibitor-induced vitiligo is a rare and unpredictable adverse event. This case report highlights the rarity of this adverse event, the dilemma related to the optimal treatment, and decisions related to continuation, holding, or switching CDK4/6 inhibitors.

Indexed as

breast cancerCDK4/6 inhibitorsribociclibskin adverse eventsvitiligovitiligo-like

Identifiers

PMID35023941
PMCPMC8743357
OpenAlexW4205356920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.