Evidence map›Paper›PMID 35023932›Full record

ArticleJournal of asthma and allergy2022

Determining Persistence with an Inhaled Corticosteroid in Asthma: Assessment Using an Objective Measurement vs the Self-Reported Foster Score.

Britt Overgaard Hedegaard, Kjell Erik Julius Håkansson, Frodi Fridason Jensen, Charlotte Suppli Ulrik, Ulla Møller Weinreich

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Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Britt Overgaard HedegaardDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark.
Kjell Erik Julius HåkanssonDepartment of Respiratory Medicine, Copenhagen University Hospital - Hvidovre, Hvidovre, Denmark.
Frodi Fridason JensenDepartment of Respiratory Medicine, Copenhagen University Hospital - Hvidovre, Hvidovre, Denmark.
Charlotte Suppli UlrikDepartment of Respiratory Medicine, Copenhagen University Hospital - Hvidovre, Hvidovre, Denmark.ORCID 0000-0001-8689-3695
Ulla Møller WeinreichDepartment of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0003-1975-3654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdherence with controller medication is a major challenge in asthma management. Thus, a reliable method of measurement is mandatory to assess adherence.

aimTo examine the test-retest reliability on adherence with inhaled corticosteroids in adults with asthma using, a self-reported adherence score (Foster score).

methodsPatients with asthma and >1 routine follow-up appointment at a university hospital outpatient clinic reported Foster scores. The objective Medication Possession Ratio (MPR) was calculated based on pharmacy redemption data and physician-prescribed doses of inhaled corticosteroids. The difference between Foster score and MPR at the first and second visit was assessed using a Bland-Altman plot, outcomes reported as limits of agreements and bias. Foster scores from both visits were used to calculate an intraclass correlation coefficient (ICC).

resultsSelf-reported adherence with asthma controller medication measured by Foster score was significantly higher than the objective MPR (p < 0.0001). The Bland-Altman plot for MPR and Foster score at the first and second visit showed upper and lower limits of agreement of 83.5 - (-1.6) and 80.9 - (-6.9) and bias was 41.0 and 37.0, respectively. Of the included patients, 93.1% reported identical Foster scores between visits, resulting in an excellent ICC of 0.92. Absolute median difference between Foster scores and MPR at first and second visit was 8.7 percentage points (p = 0.049).

conclusionFoster score shows an excellent ICC; however, its poor agreement with objective measures of adherence suggests that clinicians should not rely on Foster scores alone to assess adherence with inhaled corticosteroids in patients with asthma.

Indexed as

adherenceasthmacontroller medicationFoster scoremedication possession ratiopersistenceself-assessed adherenceself-reported outcome

Identifiers

PMID35023932
PMCPMC8743862

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