Evidence map›Paper›PMID 35023915›Full record

ArticleInternational journal of nanomedicine2022

Protective Effects of Carbon Dots Derived from

Yusheng Zhao, Yue Zhang, Hui Kong, Guoliang Cheng, Huihua Qu, Yan Zhao

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Green carbon dots derived fromFrontiers in immunology · 2024
    Article
  11. Frontiers in pharmacology · 2024
    Review
  12. Article
  13. Carbon Dots Derived fromInternational journal of nanomedicine · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Carbon Dots for the Treatment of Inflammatory Diseases: An Appraisal ofOxidative medicine and cellular longevity · 2023
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yusheng ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Yue ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Hui KongSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Guoliang ChengSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Huihua QuCentre of Scientific Experiment, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Yan ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe charcoal processed product of

aimTo explore the anti-inflammatory effects of

methodsThe physicochemical properties of ASAC-CDs including morphology, optical properties, functional groups were characterized by a series of methods, mainly including electron microscopy, optical technology and X-ray photoelectron spectroscopy. The anti-inflammatory effect of ASAC-CDs was evaluated and confirmed using acute lung injury (ALI) induced by lipopolysaccharides (LPS) in rats.

resultsThe ASAC-CDs ranged from 1.5 to 5.5 nm in diameter, with a quantum yield of 3.17%. ASAC-CDs alleviated LPS-induced inflammation, as demonstrated by reducing the levels of IL-6, IL-1β and TNF-α and increasing the contents of IL-10 in rat serum. More interestingly, ASAC-CDs reduce the content of MDA and MPO and increase the activity of SOD and the content of GSH, indicating the antioxidant activity of ASAC-CDs.

conclusionThese results demonstrate the remarkable anti-inflammatory effects of ASAC-CDs against ALI induced by LPS, which provide an important basis for the application of ASAC-CDs in clinical anti-pneumonia, and lay an experimental foundation for the research and development of novel nano-drugs.

Indexed as

Acute Lung InjuryDrugs, Chinese HerbalAnimalsCarbonLipopolysaccharidesRatsSemenCarbonDrugs, Chinese HerbalLipopolysaccharidesanti-inflammatoryArmeniacae Semen Amarum Carbonisatacarbon dotslipopolysaccharide

Identifiers

PMID35023915
PMCPMC8743863
OpenAlexW4205778861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.