Evidence map›Paper›PMID 35023564›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2022

Educating the Public on the Health Risks of Very Low Nicotine Content Cigarettes: Results From a US-Based Convenience Sample.

MacKenzie Differding, Sherri Jean Katz, Lori G Strayer, Cassidy White, Andrew A Strasser, Eric C Donny, Dorothy K Hatsukami, Dana Mowls Carroll

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

MacKenzie DifferdingMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-9147-3716
Sherri Jean KatzHubbard School of Journalism and Mass Communication, University of Minnesota, Minneapolis, MN, USA.
Lori G StrayerMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
Cassidy WhiteDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-3411-5055
Andrew A StrasserDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Eric C DonnyDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0003-3288-9652
Dorothy K HatsukamiMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-1108-2609
Dana Mowls CarrollMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-4334-9515
University of Minnesota Medical Center · USUniversity of Minnesota · USWake Forest University · USUniversity of Pennsylvania · US

Funding

VERY LOW NICOTINE CIGARETTES IN SMOKERS WITH SCHIZOPHRENIAU54DA031659 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HATSUKAMI, DOROTHY K · 2011 to 2022
$64.7M
Laying the Foundation for Personalized Smoking Cessation Treatment in the American Indian PopulationK01MD014795 · NIMHD · UNIVERSITY OF MINNESOTA · PI CARROLL, DANA MOWLS · 2020 to 2024
$684k
NIDA NIH HHS U54 DA031659NIMHD NIH HHS K01 MD014795
6 · The paper itself

Abstract

introductionUS FDA issued an advance notice of proposed rulemaking to reduce nicotine in cigarettes. To maximize the benefits of this potential standard, very low nicotine content (VLNC) cigarettes must be communicated in a way that does not result in misperceptions. AIMS AND

methodsAdults (n = 567 who smoke; n = 610 non-smokers) from an online platform were randomized to a control message previously associated with accurate addictiveness perceptions of VLNC cigarettes but health misperceptions or to one of five messages that also included messaging on nicotine morbidity effects or VLNC cigarettes morbidity or mortality effects. p value <.01 was significant.

resultsIn participants who smoke, perceived lung cancer risk (responses: 1, very little risk to 10, very high risk) if smoked VLNC cigarettes regularly was higher in conditions that communicated mortality effects of VLNC cigarettes compared to the control (7.12-7.18 vs. 5.97, p values < .01). In non-smokers, perceived lung cancer risk was higher in all five message conditions when compared with the control (7.58-8.22 vs. 6.35, p values < .01). Proportion who responded accurately (ie, False) to the statement Cigarettes with 95% less nicotine are safer than cigarettes with normal nicotine levels was higher in conditions describing VLNC morbidity or mortality effects when compared with the control in both participants who smoke (52.04-67.37% vs. 30.85%, p values < .01) and do not smoke (62.50-72.38% vs. 32.00%, p values < .01).

conclusionsMessaging on mortality effects of VLNC cigarettes (ie, cigarettes with 95% less nicotine are as deadly as current cigarettes) was associated with more accurate perceptions of the health risks of VLNC cigarettes than the control; however, misperceptions remained in one-third of participants. IMPLICATIONS: One approach to communicating a VLNC cigarette standard to the public is to include messaging on the mortality effects of VLNC cigarettes. However, further study and possible refinement of this message condition are recommended since approximately one-third of participants exposed to this message still perceived VLNC cigarettes to be safer than normal nicotine content cigarettes.

Indexed as

Behavior, AddictiveLung NeoplasmsSmoking CessationTobacco ProductsAdultHumansNicotineNicotine

Identifiers

PMID35023564
PMCPMC9048884
OpenAlexW4205934490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.