Evidence map›Paper›PMID 35023343›Full record

ArticleJournal of the American Heart Association2022

Extremity Dysfunction After Large-Bore Radial and Femoral Arterial Access.

Thomas A Meijers, Adel Aminian, Marleen van Wely, Koen Teeuwen, Thomas Schmitz, Maurits T Dirksen, Sudhir Rathore, René J van der Schaaf, Paul Knaapen, Joseph Dens and 7 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Extremity Function After Transfemoral Transcatheter Aortic Valve Implantation: A TAVI XS Sub-Study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Thomas A MeijersDepartment of Cardiology Isala Heart Center Zwolle the Netherlands.ORCID 0000-0002-4298-1607
Adel AminianDepartment of Cardiology Centre Hospitalier Universitaire de Charleroi Charleroi Belgium.ORCID 0000-0002-4667-9181
Marleen van WelyDepartment of Cardiology Radboud University Medical Center Nijmegen the Netherlands.
Koen TeeuwenDepartment of Cardiology Catharina Hospital Eindhoven the Netherlands.
Thomas SchmitzDepartment of Cardiology Elisabeth Krankenhaus Essen Germany.
Maurits T DirksenDepartment of Cardiology Northwest Clinics Alkmaar the Netherlands.ORCID 0000-0002-3263-4054
Sudhir RathoreDepartment of Cardiology Frimley Health NHS Foundation Trust Surrey United Kingdom.
René J van der SchaafDepartment of Cardiology Onze Lieve Vrouwe Gasthuis Hospital Amsterdam the Netherlands.
Paul KnaapenDepartment of Cardiology VU University Medical Center Amsterdam the Netherlands.
Joseph DensDepartment of Cardiology Hospital Oost-Limburg Genk Belgium.
Juan F IglesiasDepartment of Cardiology Geneva University Hospital Geneva Switzerland.ORCID 0000-0002-1669-6036
Pierfrancesco AgostoniDepartment of Cardiology ZNA Middelheim Antwerp Belgium.ORCID 0000-0002-1505-9369
Vincent RoolvinkDepartment of Cardiology Isala Heart Center Zwolle the Netherlands.
Miguel E LemmertDepartment of Cardiology Isala Heart Center Zwolle the Netherlands.
Renicus S HermanidesDepartment of Cardiology Isala Heart Center Zwolle the Netherlands.
Niels van RoyenDepartment of Cardiology Radboud University Medical Center Nijmegen the Netherlands.ORCID 0000-0001-6136-8640
Maarten A H van LeeuwenDepartment of Cardiology Isala Heart Center Zwolle the Netherlands.ORCID 0000-0002-9609-3728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The use of large-bore (LB) arterial access and guiding catheters has been advocated for complex percutaneous coronary intervention. However, the impact of LB transradial access (TRA) and transfemoral access (TFA) on extremity dysfunction is currently unknown. Methods and Results The predefined substudy of the COLOR (Complex Large-Bore Radial PCI) trial aimed to assess upper and lower-extremity dysfunction after LB radial and femoral access. Upper-extremity function was assessed in LB TRA-treated patients by the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire and lower-extremity function in LB TFA-treated patients by the Lower Extremity Functional Scale questionnaire. Extremity pain and effect of access site complications and risk factors on extremity dysfunction was also analyzed. There were 343 patients who completed analyzable questionnaires. Overall, upper and lower-extremity function did not decrease over time when LB TRA and TFA were used for complex percutaneous coronary intervention, as represented by the median Quick Disabilities of the Arm, Shoulder, and Hand score (6.8 at baseline and 2.1 at follow-up, higher is worse) and Lower Extremity Functional Scale score (56 at baseline and 58 at follow-up, lower is worse). Clinically relevant extremity dysfunction occurred in 6% after TRA and 9% after TFA. A trend for more pronounced upper-limb dysfunction was present in female patients after LB TRA (

Indexed as

Catheterization, PeripheralPercutaneous Coronary InterventionFemaleFemoral ArteryHumansLower ExtremityPainRadial ArteryTreatment OutcomeUpper Extremitychronic total occlusioncomplex PCIextremity dysfunctionlarge‐bore arterial access

Identifiers

PMID35023343
PMCPMC9238521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.