Evidence map›Paper›PMID 35023078›Full record

ArticleJournal of endocrinological investigation2022

Subacute thyroiditis during the COVID-19 pandemic: a prospective study.

A B Bahçecioğlu, Z C Karahan, B I Aydoğan, I A Kalkan, A Azap, M F Erdoğan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. COVID-19 pandemic and thyroid diseases.Frontiers in endocrinology · 2026
    Article
  5. Review
  6. Thyroid dysfunction in COVID-19.Nature reviews. Endocrinology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Subacute Thyroiditis Due to COVID-19 Vaccine.Journal of community hospital internal medicine perspectives · 2024
    Article
  11. Article
  12. COVID-19 vaccination and thyroiditis.Best practice & research. Clinical endocrinology & metabolism · 2023
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A B BahçecioğluDepartment of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey. begumbahceci@hotmail.com.ORCID http://orcid.org/0000-0003-0777-8934
Z C KarahanDepartment of Medical Microbiology, School of Medicine, Ankara University, Ankara, Turkey.
B I AydoğanDepartment of Endocrinology and Metabolism, Güven Hospital, Ankara, Turkey.
I A KalkanDepartment of Clinical Microbiology and Infectious Diseases, School of Medicine, Ankara University, Ankara, Turkey.
A AzapDepartment of Clinical Microbiology and Infectious Diseases, School of Medicine, Ankara University, Ankara, Turkey.
M F ErdoğanDepartment of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey.
Ankara University · TRGüven Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSubacute thyroiditis(SAT) is a destructive thyroiditis associated with viral infections. Several SAT cases associated with SARS-CoV-2 infection/vaccination were recently reported. We aimed to evaluate prospectively all cases applied to our tertiary center and their relationship with SARS-CoV-2 during 16 months of the pandemic. Cases during similar pre-pandemic period were recorded for numeric comparison.

methodsProspective study took place between March 2020 and July 2021. SAT was diagnosed by classical criteria. Swabs for SARS-CoV-2 and a wide respiratory viral panel (RV-PCR) were taken. Previous COVID-19 was assessed by SARS-CoV-2 IgM&IgG levels. Study group was divided into three as: CoV-SAT, patients who had or still have COVID-19, Vac-SAT, patients diagnosed within three months after SARS-CoV-2 vaccination and NonCoV-SAT, those not associated with COVID-19 or vaccination.

resultsOut of 64 patients, 18.8% (n = 12) was classified as CoV-SAT, 9.3% (n = 6) as Vac-SAT and 71.9% as (n = 46) NonCoV-SAT. SARS-CoV-2 RT-PCR tests on the diagnosis of SAT were negative in all, but two patients tested positive five days later, in second testing, performed upon clinical necessity. CoV-SAT and NonCoV-SAT groups were similar in terms of clinical, laboratory, and treatment characteristics. However, symptoms were milder and treatment was easier in Vac-SAT group (p = 0.006).

conclusionsTotal number of SAT cases during the pandemic period was comparable to pre-pandemic period. However, a considerable rate of SARS-CoV-2 exposure in SAT patients was established. COVID-19 presented with SAT, as the first manifestation in three cases. Vaccine-related cases developed in a shorter time period, clinical presentation was milder, and only a few required corticosteroids.

Indexed as

AdolescentAdultAgedAged, 80 and overCOVID-19COVID-19 VaccinesFemaleHumansMaleMiddle AgedPandemicsProspective StudiesThyroiditis, SubacuteYoung AdultCOVID-19 VaccinesCOVID-19PandemicSARS-CoV-2Subacute thyroiditisVaccine

Identifiers

PMID35023078
PMCPMC8754549
OpenAlexW4206072258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.