Evidence map›Paper›PMID 35022939›Full record

ArticleAIDS and behavior2022

The Relationship Between Harmful Alcohol Use and Antiretroviral Non-adherence in People Accessing HIV Treatment in Cape Town, South Africa: An Event-Level Analysis.

Alexandra L Rose, Jennifer M Belus, Tianzhou Ma, Jasper S Lee, Christine Wan, Andres De Los Reyes, John A Joska, Lena S Andersen, Bronwyn Myers, Jessica F Magidson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Alexandra L RoseDepartment of Psychology, University of Maryland, 4094 Campus Drive, College Park, MD, USA. alrose@umd.edu.ORCID http://orcid.org/0000-0001-9689-0834
Jennifer M BelusDepartment of Psychology, University of Maryland, 4094 Campus Drive, College Park, MD, USA.
Tianzhou MaDepartment of Epidemiology and Biostatistics, University of Maryland, College Park, MD, USA.
Jasper S LeeDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Christine WanDepartment of Psychology, University of Maryland, 4094 Campus Drive, College Park, MD, USA.
Andres De Los ReyesDepartment of Psychology, University of Maryland, 4094 Campus Drive, College Park, MD, USA.
John A JoskaHIV Mental Health Research Unit, University of Cape Town, Cape Town, South Africa.
Lena S AndersenGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Bronwyn MyersCurtin enAble Institute, Faculty of Health Sciences, Curtin University, Bentley, Australia.
Jessica F MagidsonDepartment of Psychology, University of Maryland, 4094 Campus Drive, College Park, MD, USA.
University of Maryland, College Park · USSouth African Medical Research Council · ZASwiss Tropical and Public Health Institute · CHUniversity of Cape Town · ZAUniversity of Copenhagen · DKUniversity of Miami · US

Funding

Hybrid Effectiveness-Implementation Trial for ART Adherence and Substance Use in HIV Care in South AfricaK23DA041901 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2016 to 2020
$1.0M
Effectiveness and implementation of pre-training interpersonal skills assessment of community health workers in South Africa to predict post-training competence in mental health careF31MH123020 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI ROSE, ALEXANDRA LEAH · 2021 to 2023
$127k
NIDA NIH HHS K23 DA041901NIDA NIH HHS K23DA041901NIMH NIH HHS F31 MH123020NIMH NIH HHS F31MH123020
6 · The paper itself

Abstract

Harmful alcohol consumption can significantly compromise adherence to antiretroviral therapy (ART). Prior research has identified aggregate relationships between alcohol use and ART non-adherence, largely relying on concurrent assessment of these domains. There is relatively limited evidence on more nuanced day-level associations between alcohol use and ART non-adherence, despite potentially important clinical implications. We recruited adults with HIV treatment adherence challenges and harmful alcohol use (n = 53) from HIV care in South Africa. We examined relationships between alcohol use and same and next day ART adherence, accounting for the role of weekends/holidays and participant demographics, including gender. Results demonstrated that ART adherence was significantly worse on weekend/holiday days. Next day adherence was significantly worse in the context of weekend alcohol use and among men. These results suggest the importance of tailoring intervention strategies to support ART adherence during weekend drinking and for men engaged in heavy episodic drinking.

Indexed as

AlcoholismAnti-HIV AgentsHIV InfectionsAdultAlcohol DrinkingAnti-Retroviral AgentsFemaleHumansMaleMedication AdherenceSouth AfricaAnti-HIV AgentsAnti-Retroviral AgentsAlcoholAntiretroviral therapyHIVSouth AfricaTreatment adherence

Identifiers

PMID35022939
PMCPMC9050741
OpenAlexW4206664878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.