Evidence map›Paper›PMID 35022927›Full record

ArticleAntonie van Leeuwenhoek2022

Study of the contribution of active defense mechanisms to ciprofloxacin tolerance in Escherichia coli growing at different rates.

Galina V Smirnova, Aleksey V Tyulenev, Nadezda G Muzyka, Oleg N Oktyabrsky

Abstract read
PubMed Publisher
In one paragraph

Article in Antonie van Leeuwenhoek, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Regulation of Cysteine Homeostasis and Its Effect onInternational journal of molecular sciences · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Galina V SmirnovaInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, ul. Goleva 13, Perm, Russia, 614081. smirnova@iegm.ru.ORCID http://orcid.org/0000-0001-6116-8147
Aleksey V TyulenevInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, ul. Goleva 13, Perm, Russia, 614081.ORCID http://orcid.org/0000-0002-0312-0409
Nadezda G MuzykaInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, ul. Goleva 13, Perm, Russia, 614081.ORCID http://orcid.org/0000-0002-4888-1471
Oleg N OktyabrskyInstitute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, ul. Goleva 13, Perm, Russia, 614081.ORCID http://orcid.org/0000-0002-9864-209X
Institute of Ecology and Genetics of Microorganisms · RU

Funding

council on grants of the president of the russian federation MK-420.2020.4
6 · The paper itself

Abstract

Using rpoS, tolC, ompF, and recA knockouts, we investigated their effect on the physiological response and lethality of ciprofloxacin in E. coli growing at different rates on glucose, succinate or acetate. We have shown that, regardless of the strain, the degree of changes in respiration, membrane potential, NAD

Indexed as

CiprofloxacinEscherichia coli ProteinsAnti-Bacterial AgentsDefense MechanismsEscherichia coliMutationAnti-Bacterial AgentsCiprofloxacinEscherichia coli ProteinsCiprofloxacinGlutathioneHydrogen sulfideMembrane potentialompF, rpoS, tolC and recA knockoutsRespirationSpecific growth rate

Identifiers

PMID35022927
OpenAlexW4225985081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.