Evidence map›Paper›PMID 35022780›Full record

ArticleThe Journal of infectious diseases2022

Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections.

Rossybelle P Amorrortu, Yayi Zhao, Neil A Fenske, Basil S Cherpelis, Jane L Messina, Anna R Giuliano, Vernon K Sondak, Michael J Schell, Sandrine Mckay-Chopin, Tarik Gheit and 3 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Rossybelle P AmorrortuDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Yayi ZhaoDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Neil A FenskeDepartment of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida, USA.
Basil S CherpelisDepartment of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida, USA.
Jane L MessinaDepartment of Anatomic Pathology, Moffitt Cancer Center, Tampa, Florida, USA.
Anna R GiulianoCenter for Immunization and Infection Research in Cancer, Moffitt Cancer Center, Tampa, Florida, USA.
Vernon K SondakDepartment of Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
Michael J SchellBiostatistics and Bioinformatics Shared Resource, Moffitt Cancer Center, Tampa, Florida, USA.
Sandrine Mckay-ChopinInternational Agency for Research on Cancer, World Health Organization, Lyon, France.
Tarik GheitInternational Agency for Research on Cancer, World Health Organization, Lyon, France.
Tim WaterboerInfections and Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Massimo TommasinoInternational Agency for Research on Cancer, World Health Organization, Lyon, France.
Dana E RollisonDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Moffitt Cancer Center · USCentre International de Recherche sur le Cancer · FRUniversity of South Florida · USGerman Cancer Research Center · DE

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Prospective study of cutaneous viral infections and non-melanoma skin cancerR01CA177586 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ROLLISON, DANA ELISE · 2014 to 2018
$3.4M
NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA177586NIH HHS R01 CA177586World Health Organization 001
6 · The paper itself

Abstract

backgroundCutaneous human papillomaviruses (cuHPV) and polyomaviruses (HPyV) have been implicated in skin cancers; however, interpretation of findings across studies is complicated by limited understanding of the natural history of these infections across normal tissue types.

methodsIn total, 675 eyebrow hair (EBH) and skin swab (SSW) samples were collected from 71 skin cancer screening patients every 6 months over 2 years and measured for presence of β-HPV, γ-HPV, and HPyV. Incidence, persistence, and clearance of cuHPV/HPyV were estimated, and risk factors associated with infection were examined.

resultsPrevalence, incidence, and persistence of β-HPV, γ-HPV, and HPyV were consistently higher in SSW than in EBH, with types 5, 24, 49, 76 and Merkel cell polyomavirus (MCPyV) having incidence rates greater than 20 per 1000 person-months. Prevalent γ-HPV EBH infections persisted more often in women (P = .024), incident β-HPV EBH infections persisted less often among individuals with history of blistering sunburn (P = .019), and prevalent MCPyV SSW infections persisted more often in those with a history of skin cancer (P = .033).

conclusionsIncidence and persistence of cuHPV/HPyV were observed in SSW and EBH; however, none of the risk factors examined were commonly associated with cuHPV/HPyV infections across normal tissue types.

Indexed as

AlphapapillomavirusPapillomavirus InfectionsPolyomavirusPolyomavirus InfectionsSkin NeoplasmsDNA, ViralFemaleHumansPapillomaviridaeDNA, Viralbasal cell carcinomacutaneous HPVincidencenatural historypersistencepolyomavirusrisk factorssquamous cell carcinoma

Identifiers

PMID35022780
PMCPMC9518839
OpenAlexW4206176969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.