Evidence map›Paper›PMID 35022674›Full record

ArticleBJS open2021

Severity grading of unexpected events in paediatric surgery: evaluation of five classification systems and the Comprehensive Complication Index (CCI®).

Omid Madadi-Sanjani, Christoph Zoeller, Joachim F Kuebler, Alejandro D Hofmann, Jens Dingemann, Soeren Wiesner, Julia Brendel, Benno M Ure

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05277441 unknown statusnot on this map

A Novel Classification for the Assessment and Grading of Unexpected Events in Pediatric Surgery: The Clavien-Madadi Classification

TypeobservationalSponsorHannover Medical SchoolRan2017 to 2023Enrolled10,000ConditionsComplication of Surgical Procedure, Complication of Anesthesia, Complication,Postoperative, Complication of Medical CareArmsNovel severity grading system of unexpected events in pediatric surgery
NCT05778019 unknown statusnot on this mapstarted 2022, after this paper: background citation

Validation of Clavien-Madadi Classification for the Grading of Unexpected Events in Pediatric Surgery

TypeobservationalSponsorHannover Medical SchoolRan2022 to 2023Enrolled20ConditionsComplication of Surgical ProcedureArmsCase Scenarios of complications to be ranked / classified according to classifications (for the severity grading of events)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Omid Madadi-SanjaniDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Christoph ZoellerDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Joachim F KueblerDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Alejandro D HofmannDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Jens DingemannDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Soeren WiesnerInstitute of Biostatistics, Hannover Medical School, Hannover, Germany.
Julia BrendelDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Benno M UreDepartment of Paediatric Surgery, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative adverse events may be associated with substantial morbidity and mortality. Numerous severity grading systems for these events have been introduced and validated but have not yet been systematically applied in paediatric surgery. This study aimed to analyse the advantages and disadvantages of these classifications in a paediatric cohort.

methodsUnexpected events associated with interventional or organizational problems in the department of paediatric surgery during 2017-2020 were prospectively documented daily for all children. Events were classified according to the Clavien-Dindo grading system during monthly morbidity and mortality conferences. All events were also classified according to five additional grading systems: T92, contracted Accordion, expanded Accordion, Memorial Sloan Kettering Cancer Center, and Comprehensive Complication Index (CCI)®.

resultsOf 6296 patients, 673 (10.7 per cent) developed adverse events and 240 (35.7 per cent) had multiple events. Overall, 1253 adverse events were identified; of these, 574 (45.2 per cent) were associated with surgical or medical interventions and 679 (54.8 per cent) included organizational problems. The grading systems demonstrated high overall correlation (rpears = 0.9), with minor differences in sentinel events. The Clavien-Dindo classification offered the most detailed assessment. However, these details had only limited additional value. The CCI® scores were correlated with other grading systems (rpears = 0.9) and were useful in analysing multiple events within individual patients.

conclusionGrading systems demonstrated similar scoring patterns for minor and sentinel events, with none being superior for unexpected events in children. However, the CCI® can be a major improvement in assessing morbidity in patients with multiple events. Its use is therefore recommended in prospective studies on paediatric surgery.

Indexed as

Postoperative ComplicationsChildCohort StudiesHumansMorbidityProspective StudiesSeverity of Illness Index

Identifiers

PMID35022674
PMCPMC8756080
OpenAlexW4205659350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.