Evidence map›Paper›PMID 35021899›Full record

ArticleAutism : the international journal of research and practice2022

A prospective study of associations between early fearfulness and perceptual sensitivity and later restricted and repetitive behaviours in infants with typical and elevated likelihood of autism.

Nisha Narvekar, Virginia Carter Leno, Greg Pasco, Mark H Johnson, Emily Jh Jones, Tony Charman

Open access · hybridAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  9. Habituation of auditory responses in young autistic and neurotypical children.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nisha NarvekarKing's College London, UK.ORCID 0000-0002-2196-4496
Virginia Carter LenoKing's College London, UK.ORCID 0000-0002-7455-5514
Greg PascoKing's College London, UK.ORCID 0000-0003-0290-6124
Mark H JohnsonBirkbeck, University of London, UK.
Emily Jh JonesBirkbeck, University of London, UK.ORCID 0000-0001-5747-9540
Tony CharmanKing's College London, UK.ORCID 0000-0003-1993-6549
King's College London · GBBirkbeck, University of London · GBUniversity of Cambridge · GB

Funding

Medical Research Council G0701484Medical Research Council MR/K021389/1Medical Research Council MR/T003057/1Wellcome TrustWellcome Trust 213608/Z/18/Z
6 · The paper itself

Abstract

lay abstractRestricted interests and repetitive behaviours are central to the diagnosis of autism and can have profound effects on daily activities and quality of life. These challenges are also linked to other co-occurring conditions such as anxiety and sensory sensitivities. Here, we looked at whether early emerging signs of anxiety and sensory problems appear before symptoms of autism by studying infants with a family history of autism, as these infants are more likely to develop autism themselves. Studying infant siblings provides an opportunity for researchers to focus on early developmental markers of autism as these infants can be followed from birth. This study found that early infant signs of anxiety (e.g. fear/shyness) predicted later perceptual sensitivity, and those infants who scored higher on fear/shyness and sensitivity were more likely to experience more persistent repetitive behaviours, but also social and communication difficulties in toddlerhood. Early signs of anxiety and perceptual sensitivity may thus relate to both later social difficulties and repetitive behaviours. These findings support the importance of further research exploring the causal links between these domains in relation to autism, resulting in increased understanding of children who go onto develop autism in the future and guiding early interventions and supports.

Indexed as

Autism Spectrum DisorderAutistic DisorderChildFearHumansInfantProspective StudiesQuality of LifeStereotyped Behaviorautismearly development pathwayselevated likelihoodrestricted and repetitive behaviourstemperament

Identifiers

PMID35021899
PMCPMC9597143
OpenAlexW4206585930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.