Evidence map›Paper›PMID 35021271›Full record

ReviewJournal of clinical neurology (Seoul, Korea)2022

Impact of General Factors on Glioma Immunotherapy.

Qilin Huang, Dongmei Wang, Guojie Yao, Hongxiang Wang

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical neurology (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Qilin Huang *Department of Neurosurgery, General Hospital of Central Theater Command of Chinese People's Liberation Army, Wuhan, China.ORCID https://orcid.org/0000-0002-8083-7518
Dongmei Wang *Department of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-1108-5866
Guojie YaoDepartment of Neurosurgery, General Hospital of Central Theater Command of Chinese People's Liberation Army, Wuhan, China. yaoguojie@hotmail.com.ORCID https://orcid.org/0000-0001-6856-2067
Hongxiang WangDepartment of Neurosurgery, Changhai Hospital, Naval Medical University, Shanghai, China. wanghongxiang27@smmu.edu.cn.ORCID https://orcid.org/0000-0003-4839-3985
Chinese People's Liberation Army · CNSecond Military Medical University · CN

Funding

National Natural Science Foundation of China 81902538Shanghai Sailing Program 19YF1448200
6 · The paper itself

Abstract

Glioma remains the most common malignant tumor in the brain and is also the most difficult to treat. Immunotherapy achieving long-lasting tumor remission in multiple cancer types has received considerable attention due to its potential to improve the treatment outcomes of patients with glioma. However, clinical trials have not yet demonstrated major improvements in prognoses, which might be attributable to the extrinsic components and intrinsic mechanisms involved in the tumor microenvironment and immune system. It is particularly noteworthy that there is emerging evidence that current routine treatment modalities and the physical and psychological characteristics of patients have different impacts on the efficacy of glioma immunotherapy. This article addresses how these factors interact with the host immune system and tumor microenvironment, and highlights their potential roles in glioma immunotherapy, with the ultimate goal of developing better immunotherapy-based personalized medicine strategies.

Indexed as

gliomaimmunotherapypsychophysiological characteristicsstandard of care

Identifiers

PMID35021271
PMCPMC8762502
OpenAlexW4206180740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.