Evidence map›Paper›PMID 35021154›Full record

ArticleAging2022

Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma.

Bing Deng, Xiaorui Chen, Lingfang Xu, Li Zheng, Xiaoqian Zhu, Junwei Shi, Lei Yang, Dian Wang, Depeng Jiang

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bing DengDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaorui ChenDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lingfang XuDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li ZhengDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaoqian ZhuDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Junwei ShiDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lei YangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Dian WangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Depeng JiangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Second Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chordin-like 1 (CHRDL1), an inhibitor of bone morphogenetic proteins(BMPs), has been recently reported to participate in the progression of numerous tumors, however, its role in lung adenocarcinoma (LUAD) remains unclear. Our study aimed to demonstrate relationship between CHRDL1 and LUAD based on data from The Cancer Genome Atlas (TCGA). Among them, CHRDL1 expression revealed promising power for distinguishing LUAD tissues form normal sample. Low CHRDL1 was correlated with poor clinicopathologic features, including high T stage (OR=0.45,

Indexed as

Databases, GeneticAdenocarcinoma of LungAgedBiomarkers, TumorEye ProteinsFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedMultivariate AnalysisNerve Tissue ProteinsSignal TransductionSurvivalTh2 CellsBiomarkers, TumorCHRDL1 protein, humanEye ProteinsNerve Tissue Proteinschordin-like 1CHRDL1lung adenocarcinomaprognosisTCGA

Identifiers

PMID35021154
PMCPMC8791215
OpenAlexW4206772208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.