Observational studyInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022
ASSOCIATION OF SMOKING AND SEVERITY OF COVID-19 INFECTION AMONG 5,889 PATIENTS IN MALAYSIA: A MULTI-CENTER OBSERVATIONAL STUDY.
Observational study in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Identification of Biomarkers and Molecular Pathways Implicated in Smoking and COVID-19 Associated Lung Cancer Using Bioinformatics and Machine Learning Approaches.International journal of environmental research and public health · 2024Article
- Effectiveness of vero cell inactivated vaccine against severe acute respiratory infections (SARI) in Sibu, Malaysia: A retrospective test-negative design.Human vaccines & immunotherapeutics · 2023Article
- Polymerase chain reaction-positivity and predictors for SARS-CoV-2 infection among diagnosed cases' in North West Ethiopia.Health science reports · 2023Article
- The predisposition of smokers to COVID-19 infection: A mini-review of global perspectives.Heliyon · 2023Review
- The pathogenetic influence of smoking on SARS-CoV-2 infection: Integrative transcriptome and regulomics analysis of lung epithelial cells.Computers in biology and medicine · 2023Article
- SARS-CoV-2 infection aggravates cigarette smoke-exposed cell damage in primary human airway epithelia.Virology journal · 2023Article
- The presence of symptoms within 6 months after COVID-19: a single-center longitudinal study.Irish journal of medical science · 2023Article
- Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance.Journal of inflammation (London, England) · 2023Review
- Association between cigarette smoking patterns and severity of COVID-19: Findings from a study in 15 private Hospitals in Indonesia.Tobacco induced diseases · 2023Article
- Assessment of the levels of antispike SARS-CoV-2 IgG antibodies and their association with clinical characteristics in cohort of patients in Saudi Arabia.Journal of family medicine and primary care · 2022Article
- Smoking status and SARS-CoV-2 infection severity among Lebanese adults: a cross-sectional study.BMC infectious diseases · 2022Article
- Post-Acute COVID-19 Sequelae in a Working Population at One Year Follow-Up: A Wide Range of Impacts from an Italian Sample.International journal of environmental research and public health · 2022Article
- Commentary on the paper: Association of smoking and severity of COVID-19 infection among 5,889 patients in Malaysia: a multi-center observational study, by Ismail N, Hassan N, Hamid MHNA, Yusoff UN, Khamal NR, Omar MA, et al. Published in Int J Infect Dis 2022;116:189-96.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Can Lung Imaging Scores and Clinical Variables Predict Severe Course and Fatal Outcome in COVID-19 Pneumonia Patients? A Single-Center Observational Study.Life (Basel, Switzerland) · 2022Article
- Examining Male Predominance of Severe COVID-19 Outcomes: A Systematic Review.Androgens: clinical research and therapeutics · 2022Review
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12 authors.
Funding
Abstract
objectiveThis study aims to investigate the association between smoking and the severity of COVID-19 infection during the initial wave of this pandemic in Malaysia.
methodsThis is a multi-center observational study using secondary hospital data collected retrospectively from February 1, 2020, until May 30, 2020. Clinical records of all real-time polymerase chain reaction (RT-PCR)-confirmed COVID-19 cases with smoking status, co-morbidities, clinical features, and disease management were retrieved. Severity was assessed by the presence of complications and outcomes of COVID-19 infection. Logistic regression was used to determine the association between COVID-19 disease severity and smoking status.
resultsA total of 5,889 COVID-19 cases were included in the analysis. Ever smokers had a higher risk of having COVID-19 complications, such as acute respiratory distress syndrome (odds ratio [OR] 1.69; 95% confidence interval [CI] 1.09-2.55), renal injury (OR 1.55; 95% CI 1.10-2.14), and acute liver injury (OR 1.33; 95% CI 1.01-1.74), compared with never smokers. However, in terms of disease outcomes, there were no differences between the two groups.
conclusionAlthough no significant association was found in terms of disease outcomes, smoking is associated with a higher risk of having complications owing to COVID-19 infection.
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