Evidence map›Paper›PMID 35020782›Full record

ArticleAmerican journal of epidemiology2022

Identifying Predictors of Opioid Overdose Death at a Neighborhood Level With Machine Learning.

Robert C Schell, Bennett Allen, William C Goedel, Benjamin D Hallowell, Rachel Scagos, Yu Li, Maxwell S Krieger, Daniel B Neill, Brandon D L Marshall, Magdalena Cerda and 1 more

Erratum issuedAbstract read
In one paragraph

Article in American journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Robert C Schell
Bennett Allen
William C Goedel
Benjamin D Hallowell
Rachel Scagos
Yu Li
Maxwell S Krieger
Daniel B Neill
Brandon D L Marshall
Magdalena Cerda
Jennifer Ahern

Funding

TRAINING IN THE DEMOGRAPHY AND ECONOMICS OF AGINGT32AG000246 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI JOSHUA R. GOLDSTEIN · 1995 to 2026
$4.6M
Reducing Drug-Related Mortality Using Predictive Analytics: A Randomized, Statewide, Community Intervention TrialR01DA046620 · NIDA · BROWN UNIVERSITY · PI CERDA, MAGDALENA, MARSHALL, BRANDON DAVID LEWIS · 2019 to 2023
$3.8M
Biomedical Big Data Training Program at UC BerkeleyT32LM012417 · NLM · UNIVERSITY OF CALIFORNIA BERKELEY · PI JORDAN, MICHAEL, NIELSEN, RASMUS · 2016 to 2020
$1.4M
NIA NIH HHS T32 AG000246NIDA NIH HHS R01 DA046620NLM NIH HHS T32 LM012417
6 · The paper itself

Abstract

Predictors of opioid overdose death in neighborhoods are important to identify, both to understand characteristics of high-risk areas and to prioritize limited prevention and intervention resources. Machine learning methods could serve as a valuable tool for identifying neighborhood-level predictors. We examined statewide data on opioid overdose death from Rhode Island (log-transformed rates for 2016-2019) and 203 covariates from the American Community Survey for 742 US Census block groups. The analysis included a least absolute shrinkage and selection operator (LASSO) algorithm followed by variable importance rankings from a random forest algorithm. We employed double cross-validation, with 10 folds in the inner loop to train the model and 4 outer folds to assess predictive performance. The ranked variables included a range of dimensions of socioeconomic status, including education, income and wealth, residential stability, race/ethnicity, social isolation, and occupational status. The R2 value of the model on testing data was 0.17. While many predictors of overdose death were in established domains (education, income, occupation), we also identified novel domains (residential stability, racial/ethnic distribution, and social isolation). Predictive modeling with machine learning can identify new neighborhood-level predictors of overdose in the continually evolving opioid epidemic and anticipate the neighborhoods at high risk of overdose mortality.

Indexed as

Drug OverdoseOpiate OverdoseAnalgesics, OpioidHumansMachine LearningResidence CharacteristicsAnalgesics, Opioidaddictionepidemiologic methodsmachine learningneighborhoodsopioidsoverdoseprediction

Identifiers

PMID35020782
PMCPMC9214774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.