Evidence map›Paper›PMID 35020527›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2022

Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway.

Ciaran A Shaughnessy, Sangya Yadav, Preston E Bratcher, Pamela L Zeitlin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ciaran A ShaughnessyDepartment of Pediatrics, National Jewish Health, Denver, Colorado.ORCID 0000-0003-2146-9126
Sangya YadavDepartment of Pediatrics, National Jewish Health, Denver, Colorado.
Preston E BratcherDepartment of Pediatrics, National Jewish Health, Denver, Colorado.ORCID 0000-0003-2240-8632
Pamela L ZeitlinDepartment of Pediatrics, National Jewish Health, Denver, Colorado.ORCID 0000-0002-2719-1834
National Jewish Health · US

Funding

Contribution of pulmonary ionocytes and neuroendocrine cells to ion transport-mediated airway surface liquid maintenanceR01HL155325 · NHLBI · NATIONAL JEWISH HEALTH · PI BRATCHER, PRESTON E · 2021 to 2025
$2.3M
Prostones as novel receptor-mediated activators of CFTR in the airwayF32HL158174 · NHLBI · NATIONAL JEWISH HEALTH · PI SHAUGHNESSY, CIARAN · 2021 to 2021
$33k
NHLBI NIH HHS F32 HL158174NHLBI NIH HHS R01 HL155325
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a genetic disease caused by mutations of the gene encoding a cAMP-activated Cl

Indexed as

Cystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorAminophenolsBenzodioxolesDinoprostoneHumansLubiprostoneMutationProstaglandinsReceptors, Prostaglandin E, EP2 SubtypeSignal TransductionAminophenolsBenzodioxolesCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorDinoprostoneLubiprostoneProstaglandinsReceptors, Prostaglandin E, EP2 SubtypeCFTR modulatorcystic fibrosisprostaglandinTrikafta

Identifiers

PMID35020527
PMCPMC8858663
OpenAlexW4206146904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.