Evidence map›Paper›PMID 35019684›Full record

ArticleMicrobiology spectrum2022

Anthranilate Acts as a Signal to Modulate Biofilm Formation, Virulence, and Antibiotic Tolerance of Pseudomonas aeruginosa and Surrounding Bacteria.

Hyeon-Ji Hwang, Xi-Hui Li, Soo-Kyoung Kim, Joon-Hee Lee

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Anthranilate ReducesAntibiotics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Transcriptome-Proteome Profiling inJournal of proteome research · 2025
    Article
  5. Review
  6. Dietary prevention of antibiotic-induced dysbiosis and mortality upon aging in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Biodegradation characteristics and genomic analysis of a newly isolated indole-degrading strain Pseudomonas aeruginosa Jade-X.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hyeon-Ji HwangDepartment of Pharmacy, College of Pharmacy, Pusan National Universitygrid.262229.f, Busan, South Korea.
Xi-Hui LiDepartment of Pharmacy, College of Pharmacy, Pusan National Universitygrid.262229.f, Busan, South Korea.
Soo-Kyoung KimDepartment of Pharmacy, College of Pharmacy, Pusan National Universitygrid.262229.f, Busan, South Korea.
Joon-Hee LeeDepartment of Pharmacy, College of Pharmacy, Pusan National Universitygrid.262229.f, Busan, South Korea.ORCID 0000-0003-4290-2945
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthranilate is a diffusible molecule produced by Pseudomonas aeruginosa and accumulates as P. aeruginosa grows. Anthranilate is an important intermediate for the synthesis of tryptophan and the Pseudomonas quinolone signal (PQS), as well as metabolized by the anthranilate dioxygenase complex (

Indexed as

BiofilmsAnti-Bacterial AgentsBacterial ProteinsHumansortho-AminobenzoatesPseudomonas aeruginosaPseudomonas InfectionsSalmonella entericaStaphylococcus aureusVirulenceanthranilic acidAnti-Bacterial AgentsBacterial Proteinsortho-Aminobenzoatesanthranilateanthranilate peakantibiotic tolerancebiofilmPseudomonas aeruginosasignaling moleculevirulence

Identifiers

PMID35019684
PMCPMC8754147
OpenAlexW4205946499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.