Evidence map›Paper›PMID 35019673›Full record

ArticleMicrobiology spectrum2022

Genetic Characteristics and Microbiological Profile of Hypermucoviscous Multidrug-Resistant Klebsiella variicola Coproducing IMP-4 and NDM-1 Carbapenemases.

Bingjie Wang, Fen Pan, Dingding Han, Wantong Zhao, Yingying Shi, Yan Sun, Chun Wang, Tiandong Zhang, Hong Zhang

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Hypermucoviscosity inJournal of bacteriology · 2026
    Review
  2. Divergent Virulence Traits inInfection and drug resistance · 2026
    Article
  3. Review
  4. Article
  5. HarnessingCurrent research in microbial sciences · 2025
    Review
  6. Article
  7. Hypermucoviscous Multidrug-ResistantPathogens (Basel, Switzerland) · 2024
    Article
  8. Coexistence of blaAnnals of clinical microbiology and antimicrobials · 2024
    Article
  9. Emergence of OXA-484-ProducingInfection and drug resistance · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bingjie Wang *Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Fen Pan *Department of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Dingding HanDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Wantong ZhaoDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Yingying ShiDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Yan SunDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Chun WangDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Tiandong ZhangDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
Hong ZhangDepartment of Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.ORCID 0000-0002-0886-9531
Shanghai Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here a hypermucoviscous, New Delhi metallo-β-lactamase 1 (NDM-1) and imipenemase 4 (IMP-4) carbapenemases-coproducing Klebsiella variicola isolate obtained from a pediatric patient. This strain was resistant to carbapenems and most other β-lactams. Although hypermucoviscous, this strain possessed attenuated virulence according to serum killing assay and Galleria mellonella infection model. Notably, two copies of

Indexed as

Genetic VariationAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsChild, PreschoolChinaDrug Resistance, Multiple, BacterialFemaleHumansKlebsiellaKlebsiella InfectionsMicrobial Sensitivity TestsPhylogenyPlasmidsVirulenceAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemscarbapenemasehypermucoviscousIMP-4ISCR1Klebsiella variicolaNDM-1whole-genome sequencing

Identifiers

PMID35019673
PMCPMC8823660
OpenAlexW4206088568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.