Evidence map›Paper›PMID 35019132›Full record

ReviewArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2022

GASTROINTESTINAL COMPLICATIONS OF CORONAVIRUS DISEASE (COVID-19).

Marcelo Augusto Fontenelle Ribeiro-Junior, Samara de Souza Augusto, Yasmin Garcia Batista Elias, Cássia Tiemi Kawase Costa, Paola Rezende Néder

Open access · diamondAbstract readReview
In one paragraph

Review in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gastrointestinal bleeding in patients with COVID-19: an integrative review.Revista do Colegio Brasileiro de Cirurgioes · 2024
    Review
  5. Article
  6. DIFFERENTIAL DIAGNOSIS BETWEEN BILIARY AND NONBILIARY ACUTE PANCREATITIS: WHAT IS THE IMPORTANCE OF LABORATORY TESTS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
  7. RESULTS OF SURGICAL TREATMENT OF COLORECTAL CANCER, ELECTIVE AND EMERGENCY, IN PATIENTS WITH COVID-19.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marcelo Augusto Fontenelle Ribeiro-JuniorDisciplina de Cirurgia Geral e do Trauma, Pontifícia Universidade Católica de São Paulo, Sorocaba, SP, Brasil.ORCID http://orcid.org/0000-0001-9826-4722
Samara de Souza AugustoUniversida de Santo Amaro, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0003-2772-9582
Yasmin Garcia Batista EliasUniversida de Santo Amaro, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-2733-4882
Cássia Tiemi Kawase CostaUniversida de Santo Amaro, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0003-4487-356X
Paola Rezende NéderUniversida de Santo Amaro, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-5198-9128
Universidade de Santo Amaro · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is currently understood that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) directly enters target cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. Accordingly, tissues with high expression levels of ACE2 are more susceptible to infection, including pulmonary alveolar epithelial cells, small intestine enterocytes, cholangiocytes, and vascular endothelial cells. Considering the atypical manifestations of COVID-19 and the challenges of early diagnosis, this review addresses the possible gastrointestinal complications of the disease.

methodThe phrase "Gastrointestinal complication of COVID" was searched in the PubMed, Medline, and SciELO databases. Due to the heterogeneity of the studies included in the present review, a narrative synthesis of the available qualitative data was performed.

resultThe literature search retrieved 28 articles, primarily case reports and case series, for the qualitative analysis of gastrointestinal complications of COVID-19, in addition to two retrospective cohort and one case-control. The studies focused on hemorrhagic, thrombotic, ischemic, and perforation complications, in addition to acute pancreatitis and pneumatosis intestinalis.

conclusionThere is a straight relationship between high expression levels of ACE2 in the gastrointestinal tract and its greater susceptibility to direct infection by SARS-CoV-2. So, it is important to consider the gastrointestinal infection manifestations for early diagnosis and treatment trying to avoid more serious complications and death.

Indexed as

COVID-19Gastrointestinal DiseasesPancreatitisAcute DiseaseEndothelial CellsHumansRetrospective StudiesSARS-CoV-2

Identifiers

PMID35019132
PMCPMC8735202
OpenAlexW4205131441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.