Evidence map›Paper›PMID 35018535›Full record

ReviewWorld journal of microbiology & biotechnology2022

Indolicidin revisited: biological activity, potential applications and perspectives of an antimicrobial peptide not yet fully explored.

Jaqueline Batista Araujo, Guilherme Sastre de Souza, Esteban Nicolas Lorenzon

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  6. Article
  7. Review
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  9. Review
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  11. Article
  12. Review
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  14. Unravelling the mechanisms causing murepavadin resistance inFrontiers in cellular and infection microbiology · 2024
    Article
  15. Review
  16. Biodegradable Polymers and Polymer Composites with Antibacterial Properties.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaqueline Batista AraujoUnidade Acadêmica Ciências da Saúde, Universidade Federal de Jataí, Jataí, Goiás, Brazil.
Guilherme Sastre de SouzaDepartamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Prêto, São Paulo, Brazil.
Esteban Nicolas LorenzonUnidade Acadêmica Ciências da Saúde, Universidade Federal de Jataí, Jataí, Goiás, Brazil. estebanlorenzon@hotmail.com.ORCID http://orcid.org/0000-0002-1645-8564

Funding

CNPq 427961/2018-1
6 · The paper itself

Abstract

The emergence of multidrug-resistant bacteria, viruses and tumors is a serious threat to public health. Among natural peptides, indolicidin, a 13-residue peptide belonging to the cathelicidin family, deserves special attention. Indolicidin has a broad spectrum of biological activity and is active against a wide range of targets, such as bacteria (Gram+  and Gram-), fungi and viruses. Here, we review the most important features of the biological activity, potential applications and perspectives of indolicidin and its analogs. Although not yet approved for commercialization, this peptide has great potential to be applied in different areas, including the medical, biomedical, food industry and other unexplored areas. To achieve this goal, a multidisciplinary team of researchers must work together to fine tune peptides that overall lead to novel analogs and formulations to combat existing and possibly future diseases.

Indexed as

AnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBacteriaBiofilmsCathelicidinsHumansMicrobial Sensitivity TestsStructure-Activity RelationshipAnti-Bacterial AgentsAntimicrobial Cationic PeptidesCathelicidinsindolicidinAntimicrobial activityIndolicidinIndolicidin analogs

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.