Evidence map›Paper›PMID 35018518›Full record

ReviewWorld journal of microbiology & biotechnology2022

Biosynthesis of vanillin by different microorganisms: a review.

Qianqian Ma, Liwen Liu, Shuo Zhao, Zhaosong Huang, Changtao Li, Shuixing Jiang, Qiang Li, Pengfei Gu

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qianqian MaSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Liwen LiuSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Shuo ZhaoSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Zhaosong HuangSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Changtao LiRZBC GROUP CO., LTD., Rizhao, 276800, Shandong, People's Republic of China.
Shuixing JiangRZBC GROUP CO., LTD., Rizhao, 276800, Shandong, People's Republic of China.
Qiang LiSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Pengfei GuSchool of Biological Science and Technology, University of Jinan, Jinan, 250022, People's Republic of China. bio_gupf@ujn.edu.cn.ORCID http://orcid.org/0000-0001-9275-9636
University of Jinan · CN

Funding

National Natural Science Foundation of China 31600066Rizhao Science and Technology Innovation Project 2020CXZX1206Science and Technology Program of University of Jinan XKY2028
6 · The paper itself

Abstract

Vanillin is a popular flavoring agent widely used around the world. Vanillin is generated by natural extraction, chemical synthesis, or tissue culture technology, but these production methods no longer meet the increasing worldwide demand for vanillin. Accordingly, a biotechnological approach may provide an effective replacement route to obtaining vanillin. Processes for environmentally friendly production of vanillin in microorganisms from different carbon sources, such as eugenol, isoeugenol, lignin, ferulic acid, sugars, and waste residues, with high productivity and yield have been developed. However, challenges remain for optimizing the vanillin biosynthesis process and further improving production titer and yield. In this review, successful and applicable strategies for increasing vanillin titer and yield in different microorganisms are summarized. Additionally, perspectives for further optimizing the production of vanillin are discussed.

Indexed as

BiotechnologyMetabolic EngineeringBenzaldehydesCoumaric AcidsEugenolFermentationFlavoring AgentsGlucoseLigninMetabolic Networks and PathwaysBenzaldehydesCoumaric AcidsEugenolferulic acidFlavoring AgentsGlucoseisoeugenolLigninvanillinFermentationGenetic engineeringMetabolic engineeringVanillin

Identifiers

PMID35018518
OpenAlexW4206583890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.