Evidence map›Paper›PMID 35018330›Full record

ArticleAccess microbiology2021

Atorvastatin does not display an antimicrobial activity on its own nor potentiates the activity of other antibiotics against

Vanessa Kornelsen, Mark Unger, Ayush Kumar

Open access · goldAbstract read
In one paragraph

Article in Access microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Virulence · 2026
    Review
  2. Review
  3. Statins, Allies against Antibiotic Resistance?Current medicinal chemistry · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vanessa KornelsenUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0002-2217-9406
Mark UngerUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-9397-0847
Ayush KumarUniversity of Manitoba, Winnipeg, Manitoba, Canada.ORCID https://orcid.org/0000-0001-6395-7932
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the current arsenal of antibiotics increasingly becoming ineffective against bacteria, there is an increasing interest in the possibility of using previously approved non-antibiotic drugs as antimicrobials. Statins have recently been investigated for their antimicrobial activity and their ability to potentially synergize with current treatment options. Atorvastatin had been shown previously to be the most promising candidate for effectivity against

Indexed as

drug developmentdrug repurposingGram-negativemultidrug resistance

Identifiers

PMID35018330
PMCPMC8742588
OpenAlexW3216862603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.