Evidence map›Paper›PMID 35018299›Full record

ArticleApplied materials today2022

Collective behavior of magnetic microrobots through immuno-sandwich assay: On-the-fly COVID-19 sensing.

Carmen C Mayorga-Martinez, Jan Vyskočil, Filip Novotný, Petr Bednar, Daniel Ruzek, Osamah Alduhaishe, Martin Pumera

Open access · greenAbstract read
In one paragraph

Article in Applied materials today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Micro- and Nano-Bots for Infection Control.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  4. Treatment of lung diseasesMaterials today. Bio · 2025
    Review
  5. Application of micro/nanorobot in medicine.Frontiers in bioengineering and biotechnology · 2024
    Review
  6. Editorial: Micro/nanorobots in nanobiotechnology.Frontiers in bioengineering and biotechnology · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Biocompatible micromotors for biosensing.Analytical and bioanalytical chemistry · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Carmen C Mayorga-MartinezCenter for Advanced Functional Nanorobots, Department of Inorganic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology Prague, Technická 5, Prague 166 28, Czech Republic.
Jan VyskočilCenter for Advanced Functional Nanorobots, Department of Inorganic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology Prague, Technická 5, Prague 166 28, Czech Republic.
Filip NovotnýCenter for Advanced Functional Nanorobots, Department of Inorganic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology Prague, Technická 5, Prague 166 28, Czech Republic.
Petr BednarVeterinary Research Institute, Hudcova 70, Brno CZ-62100, Czech Republic.
Daniel RuzekVeterinary Research Institute, Hudcova 70, Brno CZ-62100, Czech Republic.
Osamah AlduhaisheChemistry Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.
Martin PumeraCenter for Advanced Functional Nanorobots, Department of Inorganic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology Prague, Technická 5, Prague 166 28, Czech Republic.
University of Chemistry and Technology, Prague · CZKing Saud University · SAVeterinary Research Institute · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mobile self-propelled micro/nanorobots are mobile binding surface that improved the sensitivity of many biosensing system by "on-the-fly" identification and isolation of different biotargets. Proteins are powerful tools to predict infectious disease progression such as COVID-19. The main methodology used to COVID-19 detection is based on ELISA test by antibodies detection assays targeting SARS-CoV-2 virus spike protein and nucleocapside protein that represent an indirect SARS-CoV-2 detection with low sentitivy and specificity. Moreover ELISA test are limited to used external shaker to obtain homogenously immobilization of antibodies and protein on sensing platform. Here, we present magnetic microrobots that collective self-assembly through immuno-sandwich assay and they can be used as mobile platform to detect on-the-fly SARS-CoV-2 virus particle by its spike protein. The collective self-assembly of magnetic microrobots through immuno-sandwich assay enhanced its analytical performance in terms of sensitivity decreasing the detection limit of SARS-CoV-2 virus by one order of magnitude with respect to the devices previously reported. This proof-of-concept of microrobotics offer new ways to the detection of viruses and proteins of medical interest in general.

Indexed as

BiosensorCovid19Microrobots

Identifiers

PMID35018299
PMCPMC8739527
OpenAlexW4206170189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.