Evidence map›Paper›PMID 35018248›Full record

ArticleAmerican journal of cancer research2021

Diacerein, an inhibitor of IL-1β downstream mediated apoptosis, improves radioimmunotherapy in a mouse model of Burkitt's lymphoma.

Javeria Zaheer, A Ram Yu, Hyeongi Kim, Hyun Ji Kang, Min Kyoung Kang, Jae Jun Lee, Jin Su Kim

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Javeria ZaheerDivision of RI Application, Korea Institute of Radiological and Medical Sciences Seoul 01812, Republic of Korea.
A Ram YuLaboratory Animal Center, Osong Medical Innovation Foundation Osong, Chungbuk 28160, Republic of Korea.
Hyeongi KimDivision of RI Application, Korea Institute of Radiological and Medical Sciences Seoul 01812, Republic of Korea.
Hyun Ji KangDivision of RI Application, Korea Institute of Radiological and Medical Sciences Seoul 01812, Republic of Korea.
Min Kyoung KangLaboratory Animal Center, Osong Medical Innovation Foundation Osong, Chungbuk 28160, Republic of Korea.
Jae Jun LeeLaboratory Animal Center, Osong Medical Innovation Foundation Osong, Chungbuk 28160, Republic of Korea.
Jin Su KimDivision of RI Application, Korea Institute of Radiological and Medical Sciences Seoul 01812, Republic of Korea.
Korea Institute of Radiological and Medical Sciences · KROsong Medical Innovation Foundation · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoma has the characteristics of a solid tumor. Penetration of monoclonal antibodies is limited in solid tumors during radioimmunotherapy (RIT). Here, we first investigated the use of diacerein (DIA) as a combination drug to improve the penetration and therapeutic efficacy of

Indexed as

131Idiacereindrug repurposinglymphomaRadioimmunotherapyrituximab

Identifiers

PMID35018248
PMCPMC8727812
OpenAlexW4206845497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.